Compound

a ganglioside GM1b (d18:1(4E))

An anionic ganglioside anion that is the conjugate base of α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc-(1↔1')-Cer arising from deprotonation of the neuraminosyl carboxy group; major species at pH 7.3.

Definition from ChEBI (CHEBI:78568), read 2026-09-23. CC BY 4.0.

CHEBI:78568ChEBI

Open in the graph

Structure

2D depiction

Class: Organic compound, anion
Formula: C56H95N3O31R
Mass: 1306.357 g/mol
Charge: -1
SMILES: *C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O[C@]5(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O5)[C@H]4O)[C@H]3NC(C)=O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O)[C@H](O)/C=C/CCCCCCCCCCCCC
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

7 entities

7 entities reached.

0 reported hops7 assembled from the scaffold

What the reference databases state

Statements

7 statements

7 statements · 1 reference database · Subject: a ganglioside GM1b (d18:1(4E)) · Sources: Rhea

Order

a ganglioside GM1b (d18:1(4E)) is a substrate of ST6GALNAC3ProteinRhea RHEA:41968Inferred only
a ganglioside GM1b (d18:1(4E)) is a substrate of ST6GALNAC4ProteinRhea RHEA:41968Inferred only
a ganglioside GM1b (d18:1(4E)) is a substrate of ST6GALNAC5ProteinRhea RHEA:41968Inferred only
a ganglioside GM1b (d18:1(4E)) is a substrate of ST6GALNAC6ProteinRhea RHEA:41968Inferred only
a ganglioside GM1b (d18:1(4E)) is a substrate of ST8SIA1ProteinRhea RHEA:47576Inferred only
a ganglioside GM1b (d18:1(4E)) is a substrate of ST8SIA5ProteinRhea RHEA:47576Inferred only
a ganglioside GM1b (d18:1(4E)) is a substrate of ST8SIA6ProteinRhea RHEA:47576Inferred only

Reactions

5 reactions

a ganglioside GM1b (d18:1(4E))+CMP-N-acetyl-beta-neuraminatea ganglioside GD1alpha (d18:1(4E))+CMP+hydron
Catalysed by ST6GALNAC3 or ST6GALNAC6 or ST6GALNAC5 or ST6GALNAC4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:41968CC BY 4.0Reference data
a ganglioside GA1 (d18:1(4E))+CMP-N-acetyl-beta-neuraminatea ganglioside GM1b (d18:1(4E))+CMP+hydron
Catalysed by ST3GAL1 or ST3GAL4 or ST3GAL2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47560CC BY 4.0Reference data
a ganglioside GM1b (d18:1(4E))+CMP-N-acetyl-beta-neuraminatea ganglioside GD1c (d18:1(4E))+CMP+hydron
Catalysed by ST8SIA5 or ST8SIA6 or ST8SIA1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47576CC BY 4.0Reference data
a ganglioside GM1b (d18:1(4E))+watera ganglioside GA1 (d18:1(4E))+N-acetylneuraminate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:48468CC BY 4.0Reference data
a ganglioside GM1b (d18:1(4E))+UDP-N-acetyl-alpha-D-galactosamineCHEBI:141836+UDP+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:79975CC BY 4.0Reference data

Other names

8 names

Resolves to: a ganglioside GM1b (d18:1(4E))

Also called: alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11')-ceramide(1-)alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11')-N-acylsphingosinecis GM1, GM1bGanglioside GM1b (d18:1(4E))GM1b(d18:1(4E))NeuAcalpha2-3Galbeta1-3GalNAcbeta1-4Galbeta1-4Glcbeta-Cerα-N-acetylneuraminosyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl-(1→4)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1')-ceramide(1−)α-N-acetylneuraminosyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl-(1→4)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1')-N-acylsphingosine