Compound

(2R)-3-phospho-glyceroyl phosphate

Tetraanion of 3-phospho-D-glyceroyl dihydrogen phosphate arising from deprotonation of both phosphate groups.

Definition from ChEBI (CHEBI:57604), read 2026-09-23. CC BY 4.0.

CHEBI:57604ChEBI

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Structure

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A generated conformer of (2R)-3-phospho-glyceroyl phosphate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C3H4O10P2
Mass: 262.003 g/mol
Charge: -4
InChIKey: LJQLQCAXBUHEAZ-UWTATZPHSA-J
SMILES: O=C(OP(=O)([O-])[O-])[C@H](O)COP(=O)([O-])[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

11 entities

11 entities reached.

0 reported hops11 assembled from the scaffold

What the reference databases state

Statements

38 statements

38 statements · 2 reference databases · Subject: (2R)-3-phospho-glyceroyl phosphate · Sources: Human-GEM, Rhea

Order

(2R)-3-phospho-glyceroyl phosphate is converted to (2R)-3-phosphoglycerateCompoundHuman-GEM MAR04370Inferred only
(2R)-3-phospho-glyceroyl phosphate is converted to (2R)-3-phosphoglycerateCompoundHuman-GEM MAR04368Inferred only
(2R)-3-phospho-glyceroyl phosphate is converted to (2R)-3-phosphoglycerateCompoundRhea RHEA:23332Inferred only
(2R)-3-phosphoglycerate is converted to (2R)-3-phospho-glyceroyl phosphateCompoundRhea RHEA:14801Inferred only
(2R)-3-phosphoglycerate is converted to (2R)-3-phospho-glyceroyl phosphateCompoundRhea RHEA:23332Inferred only
(2R)-3-phosphoglycerate is converted to (2R)-3-phospho-glyceroyl phosphateCompoundHuman-GEM MAR04368Inferred only
(2R)-3-phospho-glyceroyl phosphate is converted to (2R)-3-phosphoglycerateCompoundRhea RHEA:14801Inferred only
(2R)-3-phospho-glyceroyl phosphate is converted to CHEBI:29052CompoundHuman-GEM MAR04373Inferred only
CHEBI:29052 is converted to (2R)-3-phospho-glyceroyl phosphateCompoundHuman-GEM MAR04373Inferred only
(2R)-3-phospho-glyceroyl phosphate is converted to D-glyceraldehyde 3-phosphateCompoundRhea RHEA:10296Inferred only
(2R)-3-phospho-glyceroyl phosphate is converted to D-glyceraldehyde 3-phosphateCompoundRhea RHEA:10300Inferred only
D-glyceraldehyde 3-phosphate is converted to (2R)-3-phospho-glyceroyl phosphateCompoundRhea RHEA:10296Inferred only

Show the remaining 26

D-glyceraldehyde 3-phosphate is converted to (2R)-3-phospho-glyceroyl phosphateCompoundRhea RHEA:10300Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of ACYP1ProteinHuman-GEM MAR04370Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of ACYP2ProteinHuman-GEM MAR04370Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of BPGMProteinRhea RHEA:17765Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of BPGMProteinHuman-GEM MAR04371Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of CRISP3ProteinHuman-GEM MAR04368Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of GAPDHProteinRhea RHEA:10300Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of GAPDHProteinHuman-GEM MAR04373Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of GAPDHSProteinHuman-GEM MAR04373Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of GAPDHSProteinRhea RHEA:10300Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGAM1ProteinRhea RHEA:17765Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGAM1ProteinHuman-GEM MAR04371Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGAM2ProteinHuman-GEM MAR04371Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGAM2ProteinRhea RHEA:17765Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGAM4ProteinHuman-GEM MAR04371Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGAM4ProteinRhea RHEA:17765Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGK1ProteinRhea RHEA:14801Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGK1ProteinHuman-GEM MAR04368Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGK2ProteinHuman-GEM MAR04368Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGK2ProteinRhea RHEA:14801Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGM2L1ProteinHuman-GEM MAR08585Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGM2L1ProteinRhea RHEA:16769Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGM2L1ProteinRhea RHEA:70899Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGM2L1ProteinRhea RHEA:70903Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGM2L1ProteinRhea RHEA:70907Inferred only
(2R)-3-phospho-glyceroyl phosphate is a substrate of PGM2L1ProteinRhea RHEA:70911Inferred only

Reactions

16 reactions

(2R)-3-phospho-glyceroyl phosphate+ADP(2R)-3-phosphoglycerate+ATP
Catalysed by CRISP3 or PGK1 or PGK2
Reaction pageReversibleBalancedEC 2.7.2.3cytosol
Human-GEM MAR04368CC BY 4.0Reference data
(2R)-3-phospho-glyceroyl phosphate+water(2R)-3-phosphoglycerate+proton+phosphate(3-)
Catalysed by ACYP1 or ACYP2
Reaction pageLeft to rightBalancedEC 3.6.1.7cytosol
Human-GEM MAR04370CC BY 4.0Reference data
(2R)-3-phospho-glyceroyl phosphateMAM00569c+proton
Catalysed by PGAM2 or PGAM1 or BPGM or PGAM4
Reaction pageLeft to rightBalancedEC 5.4.2.11, 5.4.2.4cytosol
Human-GEM MAR04371CC BY 4.0Reference data
(2R)-3-phospho-glyceroyl phosphate+proton+NADH(2-)CHEBI:29052+NAD(+)+phosphate(3-)
Catalysed by GAPDHS or GAPDH
Reaction pageReversibleBalancedEC 1.2.1.12cytosol
Human-GEM MAR04373CC BY 4.0Reference data
(2R)-3-phospho-glyceroyl phosphate+MAM01967c(2R)-3-phosphoglycerate+alpha-D-glucose 1,6-bisphosphate
Catalysed by PGM2L1
Reaction pageLeft to rightBalancedEC 2.7.1.106cytosol
Human-GEM MAR08585CC BY 4.0Reference data
D-glyceraldehyde 3-phosphate+hydrogenphosphate+NADP(3-)(2R)-3-phospho-glyceroyl phosphate+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:10296CC BY 4.0Reference data
D-glyceraldehyde 3-phosphate+hydrogenphosphate+NAD(1-)(2R)-3-phospho-glyceroyl phosphate+NADH(2-)+hydron
Catalysed by GAPDHS or GAPDH
Reaction pageReversibleBalanced
Rhea RHEA:10300CC BY 4.0Reference data
(2R)-3-phosphoglycerate+ATP(4-)(2R)-3-phospho-glyceroyl phosphate+ADP(3-)
Catalysed by PGK1 or PGK2
Reaction pageReversibleBalanced
Rhea RHEA:14801CC BY 4.0Reference data
(2R)-3-phospho-glyceroyl phosphate+alpha-D-glucose 1-phosphatealpha-D-glucose 1,6-bisphosphate+(2R)-3-phosphoglycerate+hydron
Catalysed by PGM2L1
Reaction pageLeft to rightBalanced
Rhea RHEA:16769CC BY 4.0Reference data
(2R)-3-phospho-glyceroyl phosphateCHEBI:58248+hydron
Catalysed by BPGM or PGAM2 or PGAM1 or PGAM4
Reaction pageReversibleBalanced
Rhea RHEA:17765CC BY 4.0Reference data
[phosphate](n)+(2R)-3-phospho-glyceroyl phosphate[phosphate](n+1)+(2R)-3-phosphoglycerate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:18665CC BY 4.0Reference data
(2R)-3-phosphoglycerate+GTP(2R)-3-phospho-glyceroyl phosphate+GDP
Reaction pageDirection not assertedBalanced
Rhea RHEA:23332CC BY 4.0Reference data

Show the remaining 4

Other names

2 names

Resolves to: (2R)-3-phospho-glyceroyl phosphate

Also called: 3-phosphonato-D-glyceroyl phosphate tetraanion
Systematic name: (2R)-2-hydroxy-1-oxopropane-1,3-diyl bis(phosphate)