Compound

a ganglioside GD1a

An anionic ganglioside that is the conjugate base of α-N-acetylneuraminosyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl-(1→4)-[α-N acetylneuraminosyl-(2→3)]-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1')-ceramide arising from deprotonation of the neuraminosyl carboxy groups; major species at pH 7.3.

Definition from ChEBI (CHEBI:82637), read 2026-09-23. CC BY 4.0.

CHEBI:82637ChEBI

Open in the graph

Structure

2D depiction

Class: Structural class, not a single molecule
Formula: C52H82N4O39R2
Mass: 1387.213 g/mol
Charge: -2
SMILES: *C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O[C@]5(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O5)[C@H]4O)[C@H]3NC(C)=O)[C@H](O[C@]3(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O3)[C@H]2O)[C@H](O)[C@H]1O)[C@@H](*)O
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

5 entities

5 entities reached.

0 reported hops5 assembled from the scaffold

What the reference databases state

Statements

5 statements

5 statements · 1 reference database · Subject: a ganglioside GD1a · Sources: Rhea

Order

a ganglioside GD1a is a substrate of B4GALNT1ProteinRhea RHEA:43276Inferred only
a ganglioside GD1a is a substrate of NEU2ProteinRhea RHEA:47832Inferred only
a ganglioside GD1a is a substrate of NEU3ProteinRhea RHEA:47832Inferred only
a ganglioside GD1a is a substrate of NEU4ProteinRhea RHEA:47832Inferred only
a ganglioside GD1a is a substrate of ST8SIA6ProteinRhea RHEA:48912Inferred only

Reactions

6 reactions

a ganglioside GD1a+UDP-N-acetyl-alpha-D-galactosaminea ganglioside GalNAc-GD1a+UDP+hydron
Catalysed by B4GALNT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:43276CC BY 4.0Reference data
a ganglioside GD1a+watera ganglioside GM1+N-acetylneuraminate
Catalysed by NEU4 or NEU3 or NEU2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47832CC BY 4.0Reference data
a ganglioside GM1+CMP-N-acetyl-beta-neuraminatea ganglioside GD1a+CMP+hydron
Catalysed by ST3GAL1 or ST3GAL2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:48260CC BY 4.0Reference data
a ganglioside GT1a+watera ganglioside GD1a+N-acetylneuraminate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:48472CC BY 4.0Reference data
a ganglioside GD1a+CMP-N-acetyl-beta-neuraminatea ganglioside GT1a+CMP+hydron
Catalysed by ST8SIA6
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:48912CC BY 4.0Reference data
a ganglioside GD1a+acetyl-CoACHEBI:230537+coenzyme A(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:79771CC BY 4.0Reference data

Other names

1 name

Resolves to: a ganglioside GD1a

Also called: Ganglioside GD1a