5-formimidoyltetrahydrofolate

1. 5-Formiminotetrahydrofolate:L-glutamate N-formiminotransferase

Catalysed by FTCDcytosol

1. 5-Formiminotetrahydrofolate ammonia-lyase (cyclizing)

Catalysed by FTCDcytosolOne of 2 routes

1. 5-Formiminotetrahydrofolate:L-glutamate N-formiminotransferase

Catalysed by FTCDcytosol

1. 5-Formiminotetrahydrofolate ammonia-lyase (cyclizing)
2. (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methenyltetrahydrofolate + NADH

Catalysed by FTCD, MTHFD2, MTHFD2Lcytosol

1. 5-Formiminotetrahydrofolate ammonia-lyase (cyclizing)
2. 5,10-Methenyltetrahydrofolate 5-hydrolase (decyclizing)

Catalysed by FTCD, MTHFD1cytosolOne of 5 routes

1. 5-Formiminotetrahydrofolate:L-glutamate N-formiminotransferase
2. 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
3. bile acid-CoA: amino acid N-acyltransferase

Catalysed by FTCD, SHMT1, BAATcytosol, peroxisomeOne of 28 routes

1. 5-Formiminotetrahydrofolate:L-glutamate N-formiminotransferase
2. 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
3. N(omega)-methyl-L-arginine + glyoxylate = 5-(3-methylguanidino)-2-oxopentanoate + glycine