glyoxylic acid

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

860 compounds within 3 steps: 6 in 1, 226 in 2, 628 in 3

One step

CHEBI:1146900Reach from here →
1. acetyl-CoA[m] + glyoxalate[m] + H2O[m] = CoA[m] + H+[m] + malate[m]
Catalysed by CLYBLmitochondrial matrix
pyruvateReach from here →
1. L-Alanine:glyoxylate aminotransferase
Catalysed by AGXT, AGXT2mitochondrial matrixOne of 2 routes
(S)-malateReach from here →
1. acetyl-CoA[m] + glyoxalate[m] + H2O[m] = CoA[m] + H+[m] + malate[m]
Catalysed by CLYBLmitochondrial matrix
oxalic acidReach from here →
1. Glyoxylate:oxygen oxidoreductase
Catalysed by HAO1peroxisomeOne of 2 routes
glycolateReach from here →
1. glycolate:NADP+ oxidoreductase
Catalysed by GRHPRcytosolOne of 2 routes
glycineReach from here →
1. L-Alanine:glyoxylate aminotransferase
Catalysed by AGXT, AGXT2mitochondrial matrixOne of 2 routes

Two steps

(S)-carnitineReach from here →
1. acetyl-CoA[m] + glyoxalate[m] + H2O[m] = CoA[m] + H+[m] + malate[m]
2. Carnitine O-Palmitoyltransferase
Catalysed by CLYBL, CPT1A, CPT1C, CPT1Bmitochondrial matrix, cytosolOne of 244 routes
2-hydroxybutyric acidReach from here →
1. L-Alanine:glyoxylate aminotransferase
2. transport of 2-hydroxybutyrate and pyruvate (cytosol to extracellular)
Catalysed by AGXT, AGXT2, SLC16A4, SLC16A5 and 4 more

mitochondrial matrix, extracellular space, cytosol

One of 2 routes

N(omega)-methyl-L-arginineReach from here →

Catalysed by AGXT, AGXT2mitochondrial matrix

glycoursodeoxycholateReach from here →

Catalysed by AGXT, AGXT2mitochondrial matrix, cytosolOne of 2 routes

N-(9Z-octadecenoyl)glycineReach from here →

Catalysed by AGXT, AGXT2, GLYATL3, GLYATL2mitochondrial matrix

N-octadecanoylglycineReach from here →

Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix

N-(9Z-hexadecenoyl)-glycineReach from here →

Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix

acetoacetateReach from here →

Catalysed by AGXT, AGXT2mitochondrial matrix, cytosolOne of 4 routes

N(2)-(1-hydroxy-2-oxoethyl)-dGTPReach from here →

Catalysed by GRHPR, PARK7cytosol

N(2)-(1-hydroxy-2-oxoethyl)-GMPReach from here →

Catalysed by GRHPR, PARK7cytosol

N-hexadecanoylglycineReach from here →

Catalysed by AGXT, AGXT2, GLYATL3mitochondrial matrix

N-dodecanoylglycineReach from here →

Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix

N-decanoylglycineReach from here →

Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix

N-octanoylglycineReach from here →

Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix

N(1)-(5-phospho-beta-D-ribosyl)glycinamideReach from here →

Catalysed by AGXT, AGXT2, GARTmitochondrial matrix

L-cystine-bis-glycineReach from here →

Catalysed by AGXT, AGXT2, DPEP1, DPEP2mitochondrial matrix

glycyldehydrophenylalanineReach from here →

Catalysed by AGXT, AGXT2, DPEP1mitochondrial matrix

an N-(fatty acyl)-glycineReach from here →

Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix

N-(9Z,12Z-octadecadienoyl)-glycineReach from here →

Catalysed by AGXT, AGXT2, GLYATL2mitochondrial matrix

(7Z)-octadecenoyl-CoAReach from here →

Catalysed by CLYBL, CPT1A, CPT1C, CPT1Bmitochondrial matrix, cytosolOne of 3 routes

CHEBI:15345Reach from here →

Catalysed by CLYBL, AACSmitochondrial matrix, cytosolOne of 2 routes

cholineReach from here →

Catalysed by CLYBL, CHATmitochondrial matrix, nucleus

acetylpyruvateReach from here →

Catalysed by AGXT, AGXT2, FAHD1mitochondrial matrix

all-trans-retinoic acidReach from here →

Catalysed by AGXT, AGXT2, SLC16A4, SLC16A5 and 4 moremitochondrial matrix, extracellular space, cytosolOne of 2 routes

CHEBI:15380Reach from here →

Catalysed by CLYBL, ALAS1, CPNE7mitochondrial matrixOne of 8 routes

CHEBI:15477Reach from here →

Catalysed by CLYBL, GLYAT, GLYATL2, GLYATL1mitochondrial matrixOne of 2 routes

2-methylcrotonoyl-CoAReach from here →

Catalysed by CLYBL, CPT1A, CPT1Bmitochondrial matrix, cytosolOne of 2 routes

isobutyryl-CoAReach from here →

Catalysed by CLYBL, HADHA, ACAA2, HADHBmitochondrial matrixOne of 3 routes

3-methylbut-2-enoyl-CoAReach from here →

Catalysed by CLYBL, GLYATmitochondrial matrix

isovaleryl-CoAReach from here →

Catalysed by CLYBL, GLYAT, GLYATL2, GLYATL1mitochondrial matrixOne of 3 routes

arachidonoyl-CoAReach from here →

Catalysed by CLYBL, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 11 routes

CHEBI:15519Reach from here →

Catalysed by CLYBL, ACAA1, SCP2, MYO5Bmitochondrial matrix, peroxisomeOne of 2 routes

palmitoyl-CoAReach from here →

Catalysed by CLYBL, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 11 routes

oleoyl-CoAReach from here →

Catalysed by CLYBL, CPT1A, CPT1C, CPT1Bmitochondrial matrix, cytosolOne of 11 routes

phenylacetyl-CoAReach from here →

Catalysed by CLYBLmitochondrial matrix, cytosolOne of 3 routes

propionyl-CoAReach from here →

Catalysed by CLYBL, ACSS3, ACSS2, ACSS1mitochondrial matrix, cytosolOne of 43 routes

CHEBI:15570Reach from here →

Catalysed by AGXT, AGXT2, SLC3A2, SLC7A10mitochondrial matrix, extracellular space, cytosolOne of 2 routes

L-leucineReach from here →

Catalysed by AGXT, AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 5 routes

CHEBI:15611Reach from here →

Catalysed by AGXT, AGXT2, GNMTmitochondrial matrix, cytosol

CHEBI:15650Reach from here →

Catalysed by CLYBL, ZDHHC11B, NAA10, ESCO2 and 29 moremitochondrial matrix, cytosolOne of 2 routes

CHEBI:15699Reach from here →

Catalysed by AGXT, AGXT2, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 4 routes

CHEBI:15727Reach from here →

Catalysed by CLYBL, NAA10mitochondrial matrix, cytosol

CHEBI:15746Reach from here →

Catalysed by CLYBL, SAT1, SAT2mitochondrial matrix, cytosolOne of 2 routes

malonateReach from here →

Catalysed by CLYBL, SLC25A10mitochondrial matrix, inner side of the membrane, outer side of the membraneOne of 2 routes