Compound
7,8-dihydrofolate
No description recorded for this entry yet. Everything this graph holds about 7,8-dihydrofolate is below.
Structure
No depiction stored for this entry. The InChIKey and SMILES beside this define the structure exactly.
- Class
- Organic compound, anion
- Formula
- C19H19N7O6
- Mass
- 441.404 g/mol
- Charge
- -2
- InChIKey
- OZRNSSUDZOLUSN-LBPRGKRZSA-L
- SMILES
- Nc1nc2c(c(=O)n1)N=C(CNc1ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc1)CN2
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says 7,8-dihydrofolate moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
5 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
5 entities
5 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
0 reported hops5 assembled from the scaffold
- ATICProteinUNIPROT:P31939substrate ofInferred only24 paths12 endpoints
- TYMSProteinUNIPROT:P04818substrate ofInferred only22 paths22 endpoints
- DHFRProteinUNIPROT:P00374substrate ofInferred only21 paths21 endpoints
- DHFR2ProteinUNIPROT:Q86XF0substrate ofInferred only5 paths5 endpoints
- MTO1ProteinUNIPROT:Q9Y2Z2substrate ofInferred only3 paths3 endpoints
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from 7,8-dihydrofolate: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Statements
8 statements
8 statements in 1 reference database name 7,8-dihydrofolate — Rhea. Press a relation to see only its rows; every count is the rows behind it.
- 7,8-dihydrofolate is converted to (6S)-5,6,7,8-tetrahydrofolateCompoundRhea RHEA:15009Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is converted to 7,8-dihydrofolateCompoundRhea RHEA:15009Inferred only
- 7,8-dihydrofolate is a substrate of ATICProteinRhea RHEA:62676Inferred only
- 7,8-dihydrofolate is a substrate of ATICProteinRhea RHEA:59144Inferred only
- 7,8-dihydrofolate is a substrate of DHFRProteinRhea RHEA:15009Inferred only
- 7,8-dihydrofolate is a substrate of DHFR2ProteinRhea RHEA:15009Inferred only
- 7,8-dihydrofolate is a substrate of MTO1ProteinRhea RHEA:83279Inferred only
- 7,8-dihydrofolate is a substrate of TYMSProteinRhea RHEA:12104Inferred only
Other names
2 names
Every name this graph resolves to 7,8-dihydrofolate. Searching any of them lands here.
- Also called
- dihydrofolate dianion
- Systematic name
- N-(4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamate