Compound
5-formimidoyltetrahydrofolate
Dianion of 5-formimidoyltetrahydrofolic acid arising from deprotonation of both carboxylic acid functions.
Definition from ChEBI (CHEBI:57456), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
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- Class
- Organic compound, anion
- Formula
- C20H22N8O6
- Mass
- 470.446 g/mol
- Charge
- -2
- InChIKey
- YCWUVLPMLLBDCU-STQMWFEESA-L
- SMILES
- [H]C(=N)N1c2c(nc(N)nc2=O)NC[C@@H]1CNc1ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc1
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
6 statements
6 statements · 2 reference databases · Subject: 5-formimidoyltetrahydrofolate · Sources: Human-GEM, Rhea
- 5-formimidoyltetrahydrofolate is converted to (6R)-5,10-methenyltetrahydrofolateCompoundHuman-GEM MAR03929Inferred only
- 5-formimidoyltetrahydrofolate is converted to (6R)-5,10-methenyltetrahydrofolateCompoundRhea RHEA:22736Inferred only
- (6R)-5,10-methenyltetrahydrofolate is converted to 5-formimidoyltetrahydrofolateCompoundHuman-GEM MAR03929Inferred only
- 5-formimidoyltetrahydrofolate is a substrate of FTCDProteinHuman-GEM MAR03929Inferred only
- 5-formimidoyltetrahydrofolate is a substrate of FTCDProteinHuman-GEM MAR04658Inferred only
- 5-formimidoyltetrahydrofolate is a substrate of FTCDProteinRhea RHEA:22736Inferred only
Reactions
5 reactions
(6R)-5,10-methenyltetrahydrofolate+ammonium5-formimidoyltetrahydrofolate+proton
Catalysed by FTCD
Reaction pageReversibleBalancedEC 4.3.1.4cytosol
Human-GEM MAR03929CC BY 4.0Reference data
5-formimidoyltetrahydrofolate+L-glutamate(1-)proton+N-formimidoyl-L-glutamate+5,6,7,8-tetrahydrofolic acid
Catalysed by FTCD
Reaction pageReversibleBalancedEC 2.1.2.5cytosol
Human-GEM MAR04658CC BY 4.0Reference data
5-formimidoyltetrahydrofolate+L-glutamate(1-)N-formimidoyl-L-glutamate+(6S)-5,6,7,8-tetrahydrofolate
Catalysed by FTCD
Reaction pageRight to leftBalanced
Rhea RHEA:15097CC BY 4.0Reference data
5-formimidoyltetrahydrofolate+2hydron(6R)-5,10-methenyltetrahydrofolate+ammonium
Catalysed by FTCD
Reaction pageLeft to rightBalanced
Rhea RHEA:22736CC BY 4.0Reference data
5-formimidoyltetrahydrofolate+glycineCHEBI:58479+(6S)-5,6,7,8-tetrahydrofolate
Reaction pageDirection not assertedBalanced
Rhea RHEA:24288CC BY 4.0Reference data
Other names
2 names
Resolves to: 5-formimidoyltetrahydrofolate
- Also called
- 5-formimidoyltetrahydrofolate dianion
- Systematic name
- N-[4-({[(6S)-2-amino-5-formimidoyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamate