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Proteins/UNIPROT:O95954
Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool..
Binds and promotes bundling of vimentin filaments originating from the Golgi..
Function from UniProtKB (O95954), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
44 statements
44 statements · 7 reference databases · Subject: FTCD · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
5 reactions
(6R)-5,10-methenyltetrahydrofolate+ammonium5-formimidoyltetrahydrofolate+proton
Catalysed by FTCD
Reaction pageReversibleBalancedEC 4.3.1.4cytosol
Human-GEM MAR03929CC BY 4.0Reference data
5-formimidoyltetrahydrofolate+L-glutamate(1-)proton+N-formimidoyl-L-glutamate+5,6,7,8-tetrahydrofolic acid
Catalysed by FTCD
6 names
Resolves to: FTCD
Human-GEM MAR04658CC BY 4.0Reference data
MAM01100c+L-glutamate(1-)proton+5,6,7,8-tetrahydrofolic acid+MAM10011c
Catalysed by FTCD
Reaction pageLeft to rightBalancedEC 2.1.2.5cytosol
Human-GEM MAR09726CC BY 4.0Reference data
5-formimidoyltetrahydrofolate+L-glutamate(1-)N-formimidoyl-L-glutamate+(6S)-5,6,7,8-tetrahydrofolate
Catalysed by FTCD
Reaction pageRight to leftBalanced
Rhea RHEA:15097CC BY 4.0Reference data
5-formimidoyltetrahydrofolate+2hydron(6R)-5,10-methenyltetrahydrofolate+ammonium
Catalysed by FTCD
Reaction pageLeft to rightBalanced
Rhea RHEA:22736CC BY 4.0Reference data