cholate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

414 compounds within 3 steps: 6 in 1, 95 in 2, 313 in 3

One step

2,4-dinitrophenyl-S-glutathioneReach from here →
1. solute carrier organic anion transporter (cholate)
Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes
CHEBI:15519Reach from here →
1. Cholate:CoA ligase (AMP-forming)
Catalysed by SLC27A2, SLC27A5endoplasmic reticulum
CHEBI:16856Reach from here →
1. solute carrier organic anion transporter (cholate)
Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes
deoxycholateReach from here →
1. cytochrome P450 (cholate)
Catalysed by CYP7A1cytosolOne of 2 routes
choloyl-CoAReach from here →
1. cholate + ATP + CoA = choloyl-CoA + AMP + diphosphate
Catalysed by SLC27A5
glutathioneReach from here →
1. cholate(in) + glutathione(in) + ATP + H2O = cholate(out) + glutathione(out) + ADP + phosphate + H(+)
Catalysed by ABCC4inner side of the membrane, outer side of the membrane

Two steps

CHEBI:1146900Reach from here →
1. Cholate:CoA ligase (AMP-forming)
2. bile acid-CoA: amino acid N-acyltransferase
Catalysed by SLC27A2, SLC27A5, BAATendoplasmic reticulum, peroxisomeOne of 6 routes
2-phenylpropan-2-olReach from here →
1. cholate(in) + glutathione(in) + ATP + H2O = cholate(out) + glutathione(out) + ADP + phosphate + H(+)
2. cumene hydroperoxide + 2 glutathione = 2-phenylpropan-2-ol + glutathione disulfide + H2O
Catalysed by ABCC4, CLIC2, GPX1, GPX2 and 1 moreinner side of the membrane, outer side of the membrane

a hydroxy polyunsaturated fatty acidReach from here →

Catalysed by ABCC4, GPX1, GPX2, GPX4inner side of the membrane, outer side of the membrane

S-choloyl-4'-phosphopantetheineReach from here →

Catalysed by SLC27A5, NUDT19, NUDT7

tauroursodeoxycholateReach from here →

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 5 routes

glycoursodeoxycholateReach from here →

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 5 routes

(15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →

Catalysed by ABCC4, GPX1, GPX4inner side of the membrane, outer side of the membrane

(11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoateReach from here →

Catalysed by SLCO1A2, SLCO1B3, PTGES, MGST3 and 19 moreextracellular space, cytosolOne of 5 routes

prostaglandin E3Reach from here →

Catalysed by SLCO1A2, SLCO1B3, SLCO2A1extracellular space, cytosolOne of 4 routes

prostaglandin A2Reach from here →

Catalysed by SLCO1A2, SLCO1B3, SLCO2A1extracellular space, cytosolOne of 4 routes

prostaglandin B1Reach from here →

Catalysed by SLCO1A2, SLCO1B3, SLCO2A1extracellular space, cytosolOne of 4 routes

leukotriene F4Reach from here →

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

prostaglandin A2-S-(R)-glutathioneReach from here →

Catalysed by ABCC4, GSTA1, GSTM1inner side of the membrane, outer side of the membrane

prostaglandin A2-S-(S)-glutathioneReach from here →

Catalysed by ABCC4, GSTP1, GSTM1inner side of the membrane, outer side of the membrane

prostaglandin J2-S-(R)-glutathioneReach from here →

Catalysed by ABCC4, GSTA1, GSTP1, GSTM1inner side of the membrane, outer side of the membrane

prostaglandin J2-S-(S)-glutathioneReach from here →

Catalysed by ABCC4, GSTP1, GSTM1inner side of the membrane, outer side of the membrane

deoxycholoyl-24-O-(beta-D-glucuronate)Reach from here →

Catalysed by CYP7A1, UGT2A1, UGT2A2, UGT1A3cytosol

(13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoateReach from here →

Catalysed by ABCC4, GSTM4, LTC4Sinner side of the membrane, outer side of the membrane

S-methyl glutathioneReach from here →

Catalysed by ABCC4, MMACHCinner side of the membrane, outer side of the membrane

S-adenosylglutathioneReach from here →

Catalysed by ABCC4, MMACHCinner side of the membrane, outer side of the membrane

acetylcholineReach from here →

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

CHEBI:15650Reach from here →

Catalysed by SLCO1A2, SLCO1B3, SLCO1B1extracellular space, cytosolOne of 4 routes

bromideReach from here →

Catalysed by SLCO1A2, SLCO1B3, MGST3, GSTA4 and 15 moreextracellular space, cytosolOne of 2 routes

a halide anionReach from here →

Catalysed by ABCC4, GSTT4, GSTA4, GSTZ1 and 20 moreinner side of the membrane, outer side of the membrane

lithocholic acidReach from here →

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

bilirubin IXalphaReach from here →

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

taurolithocholateReach from here →

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

CHEBI:17208Reach from here →

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosol

homocysteineReach from here →

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosol

sulfiteReach from here →

Catalysed by ABCC4, TSTD1inner side of the membrane, outer side of the membraneOne of 2 routes

L-cysteineReach from here →

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosol

urateReach from here →

Catalysed by ABCC4, SLC22A13inner side of the membrane, outer side of the membrane

methylarsonous acidReach from here →

Catalysed by ABCC4, GSTO1, GSTO2inner side of the membrane, outer side of the membrane

arsenic triglutathioneReach from here →

Catalysed by ABCC4, AS3MTinner side of the membrane, outer side of the membraneOne of 3 routes

15-deoxy-Delta(12,14)-prostaglandin J2-S-(R)-glutathioneReach from here →

Catalysed by ABCC4, MGST3inner side of the membrane, outer side of the membrane

(5S)-hydroxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoateReach from here →

Catalysed by ABCC4, GPX1, GPX4inner side of the membrane, outer side of the membrane

(12S)-hydroxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoateReach from here →

Catalysed by ABCC4, GPX1, GPX4inner side of the membrane, outer side of the membrane

(15S)-hydroxy-(11Z,13E)-eicosadienoateReach from here →

Catalysed by ABCC4, GPX1, GPX4inner side of the membrane, outer side of the membrane

(17S)-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoateReach from here →

Catalysed by ABCC4, GPX1, GPX4inner side of the membrane, outer side of the membrane

a hydroxy-1,2-diacyl-glycero-3-phosphocholineReach from here →

Catalysed by ABCC4, GPX4inner side of the membrane, outer side of the membrane

deoxycholate 3-sulfateReach from here →

Catalysed by CYP7A1, SULT2A1cytosol

3-(glutathion-S-yl)-4-hydroxynonanalReach from here →

Catalysed by ABCC4, GSTP1inner side of the membrane, outer side of the membrane

a quinolReach from here →

Catalysed by ABCC4, SQORinner side of the membrane, outer side of the membrane

5(S)-HETEReach from here →

Catalysed by SLCO1A2, SLCO1B3, GPX5, GPX1 and 7 moreextracellular space, cytosolOne of 2 routes