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Proteins/UNIPROT:P46108
Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1..
[Isoform Crk-II]: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling (By similarity)..
Function from UniProtKB (P46108), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
382 statements
382 statements · 4 reference databases · Subject: CRK · Sources: gene ontology, Hetionet, Reactome, WikiPathways · Rows fetched: 300
3 names
Resolves to: CRK