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Proteins/UNIPROT:P55201
Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac). Some HAT complexes preferentially mediate histone H3 'Lys-23' (H3K23ac) acetylation. Positively regulates the transcription of RUNX1 and RUNX2..
Function from UniProtKB (P55201), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
79 statements
79 statements · 4 reference databases · Subject: BRPF1 · Sources: gene ontology, Hetionet, Human-GEM, Reactome
1 reaction
ADP+MAM01317c+proton+phosphate(3-)ATP+MAM01676c+CHEBI:17895
Reaction pageReversibleBalance undeterminableEC 6.3.2.25cytosol
Human-GEM MAR09505CC BY 4.0Reference data
3 names
Resolves to: BRPF1