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Proteins/UNIPROT:P13987
Potent inhibitor of the complement membrane attack complex (MAC) action, which protects human cells from damage during complement activation. Acts by binding to the beta-haipins of C8 (C8A and C8B) components of the assembling MAC, forming an intermolecular beta-sheet that prevents incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore..
The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit complement membrane attack complex (MAC) assembly on cell membranes..
Function from UniProtKB (P13987), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
93 statements
93 statements · 4 reference databases · Subject: CD59 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
18 names
Resolves to: CD59