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Proteins/UNIPROT:O60381
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4..
Function from UniProtKB (O60381), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
118 statements
118 statements · 3 reference databases · Subject: HBP1 · Sources: gene ontology, Hetionet, WikiPathways
2 names
Resolves to: HBP1