ADGRG5

Orphan adhesion G protein-coupled receptor (aGPCR). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG5 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity..

Function from UniProtKB (Q8IZF4), read 2026-09-23. CC BY 4.0.