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Proteins/UNIPROT:Q9UIJ7
Mitochondrial adenylate kinase with a specific GTP:AMP phosphotransferase activity. Could also use ITP as phosphate donor. Its physiological function is to recycle GTP into GDP which is necessary for the TCA cycle in the mitochondrial matrix (Probable)..
Function from UniProtKB (Q9UIJ7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
324 statements
324 statements · 6 reference databases · Subject: AK3 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea · Rows fetched: 300
7 reactions
6 names
Resolves to: AK3
Reaction pageReversibleBalancedEC 2.7.4.3mitochondrial matrix
Human-GEM MAR04004CC BY 4.0Reference data
ADP+CHEBI:16174ATP+MAM01639c
Catalysed by AK2 or AK6 or AK1 or AK7 or AK3 or AK5 or AK9 or AK4 or AK8 or ACAD9
Reaction pageReversibleBalancedEC 2.7.4.11, 2.7.4.3cytosol
Human-GEM MAR04480CC BY 4.0Reference data
Catalysed by AK3
Reaction pageReversibleBalancedEC 2.7.4.10mitochondrial matrix
Human-GEM MAR07801CC BY 4.0Reference data
a ribonucleoside 5'-triphosphate+AMPa ribonucleoside 5'-diphosphate+ADP(3-)
Catalysed by AK3
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13749CC BY 4.0Reference data
Catalysed by AK4 or AK9 or AK3
Reaction pageDirection not assertedBalanced
Rhea RHEA:29863CC BY 4.0Reference data
Catalysed by AK3
Reaction pageDirection not assertedBalanced
Rhea RHEA:29867CC BY 4.0Reference data