prostaglandin E2

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of glycolithocholate and GSH (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. scavenger receptor class F (prostaglandin A2)
2. Transport of Prostaglandin A2, Lactate Antiport

Catalysed by SCARF2cytosol, extracellular spaceOne of 2 routes

1. prostaglandin E2(out) + a dicarboxylate(in) = prostaglandin E2(in) + a dicarboxylate(out)
2. L-erythro-7,8-dihydrobiopterin(out) + a dicarboxylate(in) = L-erythro-7,8-dihydrobiopterin(in) + a dicarboxylate(out)

Catalysed by SLC22A6, SLC22A8inner side of the membrane, outer side of the membraneOne of 2 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. gamma-glutamyltransferase (alanine)

Catalysed by SLCO1A2, SLCO1B3, GGT1, GGT5 and 4 moreextracellular space, cytosol

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and triiodothyronine (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. prostaglandin E synthase (prostaglandin E2)
2. thromboxane A synthase (12(S)-HHT)

Catalysed by PTGES, PTGES3, PTGES2, TBXAS1endoplasmic reticulum, cytosolOne of 2 routes

1. prostaglandin E2(out) + glutarate(in) = prostaglandin E2(in) + glutarate(out)
2. glutarate + succinyl-CoA = glutaryl-CoA + succinate

Catalysed by SLC22A8, SUGCTinner side of the membrane, outer side of the membraneOne of 4 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and prostaglandin E1 (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3, SLCO2A1extracellular space, cytosolOne of 6 routes

1. prostaglandin E2 + NAD(+) = 15-oxoprostaglandin E2 + NADH + H(+)
2. 13,14-dihydro-15-oxo-prostaglandin E2 + NADP(+) = 15-oxoprostaglandin E2 + NADPH + H(+)

Catalysed by HPGD, PTGR1, PTGR3, PTGR2One of 2 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and prostaglandin I2 (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3, SLCO2A1extracellular space, cytosolOne of 6 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and prostaglandin D2 (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3, SLCO2A1extracellular space, cytosolOne of 10 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. Glutathione: 15-HPETE oxidoreductase

Catalysed by SLCO1A2, SLCO1B3, GPX5, GPX1 and 7 moreextracellular space, cytosol

1. prostaglandin E synthase (prostaglandin E2)
2. thromboxane A synthase (prostaglandin H2)

Catalysed by PTGES, PTGES3, PTGES2, TBXAS1endoplasmic reticulumOne of 2 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and leukotriene A4 (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3, SLCO2A1extracellular space, cytosolOne of 4 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. (R)-S-Lactoylglutathione methylglyoxal-lyase (isomerizing)

Catalysed by SLCO1A2, SLCO1B3, GLO1, GLOD4extracellular space, cytosolOne of 2 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. alcohol dehydrogenase (formaldehyde)

Catalysed by SLCO1A2, SLCO1B3, ADH1C, ADH1A and 4 moreextracellular space, cytosol

1. prostaglandin E2(out) + a dicarboxylate(in) = prostaglandin E2(in) + a dicarboxylate(out)
2. 3',5'-cyclic GMP(out) + a dicarboxylate(in) = 3',5'-cyclic GMP(in) + a dicarboxylate(out)

Catalysed by SLC22A6inner side of the membrane, outer side of the membraneOne of 2 routes

1. transport of prostaglandin E2 (cytosol to extracellular)
2. transport of dehydroepiandrosterone sulfate (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3, SLCO1B1extracellular space, cytosolOne of 4 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. leukotriene C4 synthase (GSH)

Catalysed by SLCO1A2, SLCO1B3, LTC4Sextracellular space, cytosolOne of 6 routes

1. prostaglandin E2(out) + a dicarboxylate(in) = prostaglandin E2(in) + a dicarboxylate(out)
2. 3',5'-cyclic AMP(out) + a dicarboxylate(in) = 3',5'-cyclic AMP(in) + a dicarboxylate(out)

Catalysed by SLC22A6inner side of the membrane, outer side of the membraneOne of 2 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. Glutathione: 5-HPETE oxidoreductase

Catalysed by SLCO1A2, SLCO1B3, GPX5, GPX1 and 7 moreextracellular space, cytosolOne of 13 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and sulfotaurolithocholate (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and histamine (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and thyroxine (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. prostaglandin E2(out) + glutarate(in) = prostaglandin E2(in) + glutarate(out)
2. kynurenate(out) + glutarate(in) = kynurenate(in) + glutarate(out)

Catalysed by SLC22A8, SLC22A6inner side of the membrane, outer side of the membraneOne of 4 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. Sulfide:glutathione,quinone oxidoreductase

Catalysed by SLCO1A2, SLCO1B3, SQORextracellular space, cytosol, mitochondrial matrix

1. prostaglandin E2(out) + a dicarboxylate(in) = prostaglandin E2(in) + a dicarboxylate(out)
2. (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(out) + a dicarboxylate(in) = (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(in) + a dicarboxylate(out)

Catalysed by SLC22A6, SLC22A8inner side of the membrane, outer side of the membraneOne of 2 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of dopamine and GSH (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. prostaglandin E2(out) + 2 (S)-lactate(in) = prostaglandin E2(in) + 2 (S)-lactate(out)
2. (2S)-2-phospholactate + H2O = (S)-lactate + phosphate

Catalysed by SLCO2A1, PGPinner side of the membrane, outer side of the membraneOne of 2 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and sulfoglycolithocholate (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of prostaglandin E2 (cytosol to extracellular)
2. transport of estrone 3-sulfate (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3, SLCO1B1extracellular space, cytosolOne of 4 routes

1. prostaglandin E2(out) + a dicarboxylate(in) = prostaglandin E2(in) + a dicarboxylate(out)
2. N-benzoylglycine(out) + a dicarboxylate(in) = N-benzoylglycine(in) + a dicarboxylate(out)

Catalysed by SLC22A6, SLC22A8inner side of the membrane, outer side of the membraneOne of 2 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. glutathione gamma-glutamylaminopeptidase

Catalysed by SLCO1A2, SLCO1B3, GGTLC3, GGT1 and 4 moreextracellular space, cytosolOne of 4 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and noradrenaline (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. Resistance-Nodulation-Cell Division (Rnd) Tcdb:2.A.60.1.2

Catalysed by SLCO1A2, SLCO1B3, SLCO2A1extracellular space, cytosolOne of 4 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and ursodeoxycholate (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosolOne of 4 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and prostaglandin G2 (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3, SLCO2A1extracellular space, cytosolOne of 4 routes

1. prostaglandin E2(out) + glutarate(in) = prostaglandin E2(in) + glutarate(out)
2. 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + glutarate(in) = 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + glutarate(out)

Catalysed by SLC22A8, SLC22A24inner side of the membrane, outer side of the membraneOne of 2 routes

1. prostaglandin E synthase (prostaglandin E2)
2. prostaglandin H2 = (12S)-hydroxy-(5Z,8E,10E)-heptadecatrienoate + malonaldehyde

Catalysed by PTGES, PTGES3, PTGES2, TBXAS1 and 1 moreendoplasmic reticulum

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and thromboxane B2 (cytosol to extracellular)

Catalysed by SLCO1A2, SLCO1B3, SLCO1B1extracellular space, cytosolOne of 6 routes

1. prostaglandin E synthase (prostaglandin E2)
2. prostaglandin H2 + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxyprostaglandin H2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by PTGES, PTGES3, PTGES2, CYP4F8endoplasmic reticulum

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. solute carrier organic anion transporter (GSH)

Catalysed by SLCO1A2, SLCO1B3, SLC7A9extracellular space, cytosolOne of 4 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of arachidonate and GSH (cytosol to extracellular)
3. Utilized Transport

Catalysed by SLCO1A2, SLCO1B3extracellular space, cytosol, endoplasmic reticulumOne of 2 routes

1. transport of GSH and prostaglandin E2 (cytosol to extracellular)
2. transport of GSH and leukotriene E4 (cytosol to extracellular)
3. N-acetyl-LTE4 to leukotriene E4 conversion

Catalysed by SLCO1A2 and 31 more