alpha-D-galactose 1-phosphate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

119 compounds within 3 steps: 4 in 1, 46 in 2, 69 in 3

Three steps

an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GlcNAc derivativeReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)
3. a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose = an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GlcNAc derivative + GDP + H(+)
Catalysed by GALT, B3GALT2, B3GALT1, FUT2
an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivativeReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)
3. a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose = an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP + H(+)
Catalysed by GALT, B4GALT3, B4GALT2, B4GALT1 and 2 more
an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivativeReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)
3. a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)
Catalysed by GALT, B4GALT3, B4GALT2, B4GALT1 and 4 moreOne of 2 routes
an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivativeReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)
3. a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+)
Catalysed by GALT, B4GALT3, B4GALT2, B4GALT1 and 3 more
a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-N-acetyl-beta-D-GlcNAc derivativeReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-N-acetyl-beta-D-GlcNAc derivative + UDP + H(+)
Catalysed by GALT, SLC35A2, GCNT3, GCNT2inner side of the membrane, outer side of the membrane
an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivativeReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + UDP + H(+)
3. a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)
Catalysed by GALT, C1GALT1, ST3GAL1, ST3GAL4 and 1 more
genistein 7-O-beta-D-glucosideReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
3. genistein + UDP-alpha-D-glucose = genistein 7-O-beta-D-glucoside + UDP + H(+)
Catalysed by GALT, UGT3A2, UGT3A1
a globoside GlcNAc-(beta1->6)-GalGb4CerReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a globoside GalGb4Cer + UDP-N-acetyl-alpha-D-glucosamine = a globoside GlcNAc-(beta1->6)-GalGb4Cer + UDP + H(+)
Catalysed by GALT, SLC35A2, GCNT1inner side of the membrane, outer side of the membrane
a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivativeReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + UDP + H(+)
3. a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)
Catalysed by GALT, C1GALT1, ST6GALNAC1, ST6GALNAC2
a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E))Reach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. beta-1,4-galactosyltransferase (lc3Cer)
3. a neolactoside nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + UDP + H(+)
Catalysed by GALT, B4GALT3, B4GALT4, B4GALT2 and 2 morecytosolOne of 2 routes
beta-D-glucoseReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate
3. D-glucose 1-epimerase
Catalysed by GALT, IMPA2, IMPA1, GALMcytosol
CHEBI:16174Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate
3. dATP:D-glucose 6-phosphotransferase
Catalysed by GALT, IMPA2, IMPA1, HK1 and 3 morecytosol
D-glucono-1,5-lactoneReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate
3. D-glucose + NAD(+) = D-glucono-1,5-lactone + NADH + H(+)
Catalysed by GALT, IMPA2, IMPA1, H6PDOne of 2 routes
(R)-glycerateReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. (2R)-3-phospho-glyceroyl phosphate + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + (2R)-3-phosphoglycerate + H(+)
3. (R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H(+)
Catalysed by GALT, PGM2L1, GLYCTK
a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))Reach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. glucosylceramide pool to LacCer pool conversion
3. UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase (LacCer pool)
Catalysed by GALT, ALG1L2, B4GALT5, B3GALT2 and 32 morecytosol, endoplasmic reticulumOne of 4 routes
aldehydo-N-acetyl-D-mannosamineReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. UDP-N-acetyl-alpha-D-glucosamine + H2O = aldehydo-N-acetyl-D-mannosamine + UDP + H(+)
Catalysed by GALT, SLC35A2, GNEinner side of the membrane, outer side of the membrane
CHEBI:17808Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate
3. ITP:D-glucose 6-phosphotransferase
Catalysed by GALT, IMPA2, IMPA1, HK1 and 3 morecytosol
D-glucitolReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate
3. Aldehyde Reductase
Catalysed by GALT, IMPA2, IMPA1cytosolOne of 3 routes
a globoside Gb4Cer (d18:1(4E))Reach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. alpha 1,4-galactosyltransferase (P blood group) (LacCer pool)
3. globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase (globotriaosylceramide)
Catalysed by GALT, A4GALTcytosolOne of 5 routes
D-glucosyl-N-acylsphingosineReach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. glucosylceramide pool to LacCer pool conversion
3. beta-D-Galactosyl-1,4-beta-D-glucosylceramide galactohydrolase
Catalysed by GALT, ALG1L2, B4GALT5, B3GALT2 and 36 morecytosol, endoplasmic reticulum, lysosome
a ganglioside beta-D-GlcNAc-(1->6)-GA1Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a ganglioside GA1 + UDP-N-acetyl-alpha-D-glucosamine = a ganglioside beta-D-GlcNAc-(1->6)-GA1 + UDP + H(+)
Catalysed by GALT, SLC35A2, GCNT1inner side of the membrane, outer side of the membrane
cholesteryl 3-beta-D-galactosideReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
3. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-galactoside + an N-acylsphing-4-enine
Catalysed by GALT, UGT8, GBA1, GBA2
a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enineReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
3. an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
Catalysed by GALT, UGCG
a lysoGb3(d18:1(4E))Reach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. alpha 1,4-galactosyltransferase (P blood group) (LacCer pool)
3. a globoside Gb3Cer (d18:1(4E)) + H2O = a lysoGb3(d18:1(4E)) + a fatty acid
Catalysed by GALT, A4GALT, ASAH1cytosol
a lysoGb3Reach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-alpha-D-galactose = a globoside Gb3Cer + UDP + H(+)
3. a globoside Gb3Cer + H2O = a lysoGb3 + a fatty acid
Catalysed by GALT, A4GALT, ASAH1
an N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-galactosyl derivativeReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a beta-D-galactoside + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-galactosyl derivative + UDP + H(+)
Catalysed by GALT, SLC35A2, A4GNTinner side of the membrane, outer side of the membrane
beta-D-galactoseReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. D-glucose + UDP-alpha-D-galactose = lactose + UDP + H(+)
3. lactose + H2O = beta-D-galactose + D-glucose
Catalysed by GALT, B4GALT2, B4GALT1, LCT
a ganglioside GA2 (d18:1(4E))Reach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. glucosylceramide pool to LacCer pool conversion
3. beta-1,4-N-acetyl-galactosaminyltransferase (LacCer pool)
Catalysed by GALT, ALG1L2, B4GALT5, B3GALT2 and 33 morecytosol, endoplasmic reticulumOne of 4 routes
alpha-D-galactoseReach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. glucosylceramide pool to LacCer pool conversion
3. beta-D-Galactosyl-1,4-beta-D-glucosylceramide galactohydrolase
Catalysed by GALT, ALG1L2, B4GALT5, B3GALT2 and 36 morecytosol, endoplasmic reticulum, lysosomeOne of 14 routes
an N-acetyl-alpha-D-galactosaminyl derivativeReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + UDP + H(+)
3. an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + UDP + H(+)
Catalysed by GALT, C1GALT1
(2S)-naringenin 7-O-beta-D-glucosideReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
3. (2S)-naringenin + UDP-alpha-D-glucose = (2S)-naringenin 7-O-beta-D-glucoside + UDP + H(+)
Catalysed by GALT, UGT3A2
a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E))Reach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. beta-1,4-galactosyltransferase (lc3Cer)
3. a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)
Catalysed by GALT, B4GALT3, B4GALT4, B4GALT2 and 3 morecytosol
alpha-L-fucosyl-(1->2)- beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enineReach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase (lc3Cer)
3. type 1 galactoside alpha-(1,2)-fucosyltransferase (GDP-L-fucose)
Catalysed by GALT, B3GALT2, B3GALT5, B3GALT1 and 2 morecytosolOne of 2 routes
a fatty acidReach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. alpha 1,4-galactosyltransferase (P blood group) (LacCer pool)
3. a globoside Gb3Cer (d18:1(4E)) + H2O = a lysoGb3(d18:1(4E)) + a fatty acid
Catalysed by GALT, A4GALT, ASAH1cytosolOne of 2 routes
N-acetylneuraminateReach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. beta-1,3-galactosyltransferase (GM2)
3. a ganglioside GM1 (d18:1(4E)) + H2O = a ganglioside GA1 (d18:1(4E)) + N-acetylneuraminate
Catalysed by GALT, B3GALT4, NEU3cytosolOne of 3 routes
D-glucopyranose 6-phosphateReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate
3. ATP:D-glucose 6-phosphotransferase
Catalysed by GALT, IMPA2, IMPA1, HK1 and 4 morecytosolOne of 5 routes
daidzein 7-O-beta-D-glucosideReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
3. daidzein + UDP-alpha-D-glucose = daidzein 7-O-beta-D-glucoside + UDP
Catalysed by GALT, UGT3A2
N-acetyl-beta-neuraminic acidReach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. beta-1,3-galactosyltransferase (GM2)
3. Sialidase, Cytosol (Neu2)
Catalysed by GALT, B3GALT4, NEU2cytosolOne of 3 routes
an N-acylsphing-4-enineReach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. UDP-alpha-D-galactose:N-acylsphingosine D-galactosyltransferase
3. galactosylceramidase (D-galactosyl-N-acylsphingosine)
Catalysed by GALT, UGT8, GALCcytosol, lysosomeOne of 4 routes
a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)
Catalysed by GALT, SLC35A2, PIGAinner side of the membrane, outer side of the membrane
(2R)-3-phospho-glyceroyl phosphateReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. (2R)-3-phospho-glyceroyl phosphate + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + (2R)-3-phosphoglycerate + H(+)
3. ATP:3-phospho-D-glycerate 1-phosphotransferase
Catalysed by GALT, PGM2L1, PGK1, PGK2 and 1 morecytosolOne of 2 routes
beta-D-fructose 6-phosphateReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
3. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate
Catalysed by GALT, PGM1, PGM2, GPI
sphing-4-enineReach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase
3. UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase
Catalysed by GALTcytosolOne of 2 routes
N-acetyl-alpha-D-glucosamine 1-phosphateReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
3. UDP-N-acetyl-alpha-D-glucosamine + H2O = N-acetyl-alpha-D-glucosamine 1-phosphate + UMP + 2 H(+)
Catalysed by GALT, SLC35A2, ENPP3inner side of the membrane, outer side of the membrane
(2R)-2-phosphoglycerateReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. (2R)-3-phospho-glyceroyl phosphate + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + (2R)-3-phosphoglycerate + H(+)
3. D-phosphoglycerate 2,3-phosphomutase
Catalysed by GALT, PGM2L1, BPGM, PGAM2 and 2 morecytosolOne of 2 routes
a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))Reach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. beta-1,4-galactosyltransferase (lc3Cer)
3. ST3 beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by GALT, B4GALT3, B4GALT4, B4GALT2 and 2 morecytosolOne of 2 routes
a ganglioside GM3 (d18:1(4E))Reach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. glucosylceramide pool to LacCer pool conversion
3. ST3 beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by GALT, ALG1L2, B4GALT5, B3GALT2 and 33 morecytosol, endoplasmic reticulumOne of 3 routes
D-glucose 6-phosphateReach from here →
1. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
2. alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate
3. D-glucose + ADP = D-glucose 6-phosphate + AMP + H(+)
Catalysed by GALT, IMPA2, IMPA1, ADPGKOne of 2 routes
a ganglioside GM2 (d18:1(4E))Reach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. beta-1,3-galactosyltransferase (GM2)
3. beta-galactosidase (GM1)
Catalysed by GALT, B3GALT4, LCT, GLB1 and 2 morecytosolOne of 5 routes
an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enineReach from here →
1. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
2. UDP-alpha-D-galactose:N-acylsphingosine D-galactosyltransferase
3. 3'-Phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase
Catalysed by GALT, UGT8, GAL3ST1cytosol, lysosomeOne of 2 routes