D-glucosyl-N-acylsphingosine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

232 compounds within 3 steps: 3 in 1, 32 in 2, 197 in 3

One step

a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))Reach from here →
1. glucosylceramide pool to LacCer pool conversion
Catalysed by ALG1L2, B4GALT5, B3GALT2, B4GALT3 and 31 moreendoplasmic reticulumOne of 4 routes
D-glucoseReach from here →
1. D-Glucosyl-N-acylsphingosine glucohydrolase
Catalysed by GBA1, GBA3, GBA2cytosolOne of 3 routes
an N-acylsphing-4-enineReach from here →
1. D-Glucosyl-N-acylsphingosine glucohydrolase
Catalysed by GBA1, GBA3, GBA2cytosolOne of 3 routes

Two steps

Three steps

CHEBI:1146900Reach from here →
Catalysed by GBA1, GBA3, GBA2, ASAH1 and 7 morecytosol, Golgi apparatus, mitochondrial matrixOne of 17 routes
AReach from here →

FADS3

cytosol

beta-D-glucoseReach from here →

Catalysed by GBA1, GBA3, GBA2, GALMcytosol

cholesterolReach from here →

Catalysed by GBA1, GBA3, GBA2cytosolOne of 3 routes

CHEBI:16174Reach from here →

Catalysed by GBA1, GBA3, GBA2, HK1 and 3 morecytosol

D-glucono-1,5-lactoneReach from here →

Catalysed by GBA1, GBA3, GBA2, H6PDcytosolOne of 2 routes

a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))Reach from here →

Catalysed by ALG1L2, B4GALT5, B3GALT2, B4GALT3 and 31 moreendoplasmic reticulum, cytosolOne of 3 routes

a sphingomyelinReach from here →

Catalysed by GBA1, GBA3, GBA2, SGMS1 and 1 morecytosol, Golgi apparatusOne of 8 routes

lactoseReach from here →

Catalysed by GBA1, GBA3, GBA2, B4GALT2 and 1 morecytosol

CHEBI:17808Reach from here →

Catalysed by GBA1, GBA3, GBA2, HK1 and 3 morecytosol

a 1,2-diacyl-sn-glycerolReach from here →

Catalysed by GBA1, GBA3, GBA2, SGMS1 and 1 morecytosol, Golgi apparatusOne of 6 routes

D-glucitolReach from here →

Catalysed by GBA1, GBA3, GBA2cytosolOne of 3 routes

a globoside Gb3Cer (d18:1(4E))Reach from here →

Catalysed by ALG1L2, B4GALT5, B3GALT2, B4GALT3 and 32 moreendoplasmic reticulum, cytosolOne of 3 routes

a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enineReach from here →

Catalysed by GBA1, GBA3, GBA2, UGT8cytosolOne of 2 routes

a beta-D-xylosyl-(1<->1')-N-acylsphing-4-enineReach from here →

Catalysed by GBA1, GBA3, GBA2cytosolOne of 2 routes

a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enineReach from here →

Catalysed by GBA1, GBA3, GBA2, UGCGcytosolOne of 2 routes

a ganglioside GA2 (d18:1(4E))Reach from here →

Catalysed by ALG1L2, B4GALT5, B3GALT2, B4GALT3 and 32 moreendoplasmic reticulum, cytosolOne of 3 routes

alpha-D-galactoseReach from here →

Catalysed by ALG1L2, B4GALT5, B3GALT2, B4GALT3 and 35 moreendoplasmic reticulum, lysosome

a fatty acidReach from here →

Catalysed by GBA1, GBA3, GBA2, NAAA and 5 morecytosol

fatty acidReach from here →

Catalysed by GBA1, GBA3, GBA2, ASAH1cytosol, lysosome

alpha-lactoseReach from here →

Catalysed by GBA1, GBA3, GBA2, B4GALT2 and 2 morecytosol, Golgi apparatus

D-glucopyranose 6-phosphateReach from here →

Catalysed by GBA1, GBA3, GBA2, HK1 and 4 morecytosolOne of 5 routes

an isogloboside iGb3Cer (d18:1(4E))Reach from here →

Catalysed by ALG1L2, B4GALT5, B3GALT2, B4GALT3 and 32 moreendoplasmic reticulum

an N-acylsphing-4-enine 1-phosphateReach from here →

Catalysed by GBA1, GBA3, GBA2, AGK and 1 morecytosol

sphing-4-enineReach from here →

Catalysed by GBA1, GBA3, GBA2, ASAH1 and 3 morecytosol, Golgi apparatusOne of 4 routes

an acyl-CoAReach from here →

Catalysed by GBA1, GBA3, GBA2, ASAH1 and 3 morecytosol, Golgi apparatusOne of 2 routes

a ganglioside GM3 (d18:1(4E))Reach from here →

Catalysed by ALG1L2, B4GALT5, B3GALT2, B4GALT3 and 32 moreendoplasmic reticulum, cytosolOne of 3 routes

D-glucose 6-phosphateReach from here →

Catalysed by GBA1, GBA3, GBA2, ADPGKcytosolOne of 2 routes

an N-acylsphing-4-enine 1-phosphoethanolamineReach from here →

Catalysed by GBA1, GBA3, GBA2, SGMS1 and 2 morecytosol

beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enineReach from here →

Catalysed by ALG1L2, B4GALT5, B3GALT2, B4GALT3 and 32 moreendoplasmic reticulum

1,2-dihexadecanoyl-sn-glycerolReach from here →

Catalysed by GBA1, GBA3, GBA2, SGMS2cytosol

1-(9Z-octadecenoyl)-2-acyl-sn-3-glycerolReach from here →

Catalysed by GBA1, GBA3, GBA2, SGMS1 and 1 morecytosol

Catalysed by GBA1, GBA3, GBA2, CH25Hcytosol

an acyl-4'-phosphopantetheineReach from here →

Catalysed by GBA1, GBA3, GBA2, ASAH1 and 6 morecytosol, Golgi apparatus

cholesterol sulfateReach from here →

Catalysed by GBA1, GBA3, GBA2, SULT2B1 and 1 morecytosol

a 3-(acyloxy)acyl derivative of bacterial toxinReach from here →

Catalysed by GBA1, GBA3, GBA2, NAAA and 6 morecytosol

(11Z,14Z,17Z-eicosatrienoyl)-cholesterolReach from here →

Catalysed by GBA1, GBA3, GBA2, LCATcytosol

cholesteryl (7Z)-octadecenoateReach from here →

Catalysed by GBA1, GBA3, GBA2, SOAT1cytosol

(7Z)-octadecenoyl-CoAReach from here →

Catalysed by GBA1, GBA3, GBA2, ASAH1 and 3 morecytosol, Golgi apparatus

pyruvateReach from here →

Catalysed by GBA1, GBA3, GBA2, HK1 and 5 morecytosol

arachidonoyl-CoAReach from here →

Catalysed by GBA1, GBA3, GBA2, ASAH1 and 3 morecytosol, Golgi apparatus

palmitoyl-CoAReach from here →

Catalysed by GBA1, GBA3, GBA2, ASAH1 and 3 morecytosol, Golgi apparatus

oleoyl-CoAReach from here →

Catalysed by GBA1, GBA3, GBA2, ASAH1 and 3 morecytosol, Golgi apparatus

hexadecanoic acidReach from here →

Catalysed by GBA1, GBA3, GBA2, ASAH1cytosol, lysosome, extracellular spaceOne of 12 routes

1-acylglycerone 3-phosphateReach from here →

Catalysed by GBA1, GBA3, GBA2, ASAH1 and 4 morecytosol, Golgi apparatus

keto-D-fructose 6-phosphateReach from here →

Catalysed by GBA1, GBA3, GBA2, HK1 and 5 morecytosol