Compound

a globoside Gb4Cer (d18:1(4E))

A glycotetraosylceramide having N-acetyl-β-D-galactosaminyl-(1→3)-α-D-galactosyl-(1→4)-β-D-galactosyl-(1→4)-β-D-glucose as the tetrasaccharide component.

Definition from ChEBI (CHEBI:18259), read 2026-09-23. CC BY 4.0.

CHEBI:18259ChEBI

Open in the graph

Structure

2D depiction

Class: Organic compound
Formula: C45H79N2O23R
Mass: 1016.108 g/mol
Charge: 0
SMILES: *C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4NC(C)=O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O)[C@H](O)/C=C/CCCCCCCCCCCCC
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

4 entities

4 entities reached.

0 reported hops4 assembled from the scaffold

What the reference databases state

Statements

12 statements

12 statements · 2 reference databases · Subject: a globoside Gb4Cer (d18:1(4E)) · Sources: Human-GEM, Rhea

Order

a globoside Gb4Cer (d18:1(4E)) is a substrate of B3GALT5ProteinRhea RHEA:41996Inferred only
a globoside Gb4Cer (d18:1(4E)) is a substrate of B3GALT5ProteinHuman-GEM MAR00809Inferred only
a globoside Gb4Cer (d18:1(4E)) is a substrate of B3GALT5ProteinHuman-GEM MAR08150Inferred only
a globoside Gb4Cer (d18:1(4E)) is a substrate of B3GNT3ProteinHuman-GEM MAR08194Inferred only
a globoside Gb4Cer (d18:1(4E)) is a substrate of GBGT1ProteinHuman-GEM MAR08198Inferred only
a globoside Gb4Cer (d18:1(4E)) is a substrate of GBGT1ProteinHuman-GEM MAR00810Inferred only
a globoside Gb4Cer (d18:1(4E)) is a substrate of HEXAProteinHuman-GEM MAR00807Inferred only
a globoside Gb4Cer (d18:1(4E)) is a substrate of HEXAProteinHuman-GEM MAR00808Inferred only
a globoside Gb4Cer (d18:1(4E)) is a substrate of HEXBProteinHuman-GEM MAR00808Inferred only
a globoside Gb4Cer (d18:1(4E)) is a substrate of HEXBProteinHuman-GEM MAR00807Inferred only
a globoside Gb4Cer (d18:1(4E)) is a substrate of HEXDProteinHuman-GEM MAR00808Inferred only
a globoside Gb4Cer (d18:1(4E)) is a substrate of HEXDProteinHuman-GEM MAR00807Inferred only

Reactions

22 reactions

a globoside Gb3Cer (d18:1(4E))+MAM03110ca globoside Gb4Cer (d18:1(4E))+proton+UDP
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.79GO:0005829
Human-GEM MAR00805CC BY 4.0Reference data
a globoside Gb3Cer (d18:1(4E))+MAM03110la globoside Gb4Cer (d18:1(4E))+proton+UDP
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.79GO:0005764
Human-GEM MAR00806CC BY 4.0Reference data
a globoside Gb4Cer (d18:1(4E))+watera globoside Gb3Cer (d18:1(4E))+MAM02525c
Catalysed by HEXB or HEXD or HEXA
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.52GO:0005829
Human-GEM MAR00807CC BY 4.0Reference data
a globoside Gb4Cer (d18:1(4E))+watera globoside Gb3Cer (d18:1(4E))+MAM02525l
Catalysed by HEXB or HEXD or HEXA
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.52GO:0005764
Human-GEM MAR00808CC BY 4.0Reference data
a globoside Gb4Cer (d18:1(4E))+CHEBI:67119MAM01912c+proton+UDP
Catalysed by B3GALT5
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-GO:0005829
Human-GEM MAR00809CC BY 4.0Reference data
a globoside Gb4Cer (d18:1(4E))+MAM03110cproton+MAM02197c+UDP
Catalysed by GBGT1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.88GO:0005829
Human-GEM MAR00810CC BY 4.0Reference data
water+MAM02197ca globoside Gb4Cer (d18:1(4E))+MAM02525c
Catalysed by NAGA
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.49GO:0005829
Human-GEM MAR00811CC BY 4.0Reference data
a globoside Gb3Cer (d18:1(4E))+MAM03110ga globoside Gb4Cer (d18:1(4E))+proton+UDP
Catalysed by B3GALNT1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.79GO:0005794
Human-GEM MAR08149CC BY 4.0Reference data
a globoside Gb4Cer (d18:1(4E))+CHEBI:67119MAM01912g+proton+UDP
Catalysed by B3GALT5
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-GO:0005794
Human-GEM MAR08150CC BY 4.0Reference data
a globoside Gb4Cer (d18:1(4E))+MAM02525gMAM01391g+water
Catalysed by B3GNT3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-GO:0005794
Human-GEM MAR08194CC BY 4.0Reference data
MAM01391l+proton+UDPa globoside Gb4Cer (d18:1(4E))+MAM03110l
Reaction pageLeft to rightBalance undeterminableGO:0005764
Human-GEM MAR08197CC BY 4.0Reference data
a globoside Gb4Cer (d18:1(4E))+MAM03110gMAM01324g+proton+UDP
Catalysed by GBGT1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.88GO:0005794
Human-GEM MAR08198CC BY 4.0Reference data

Show the remaining 10

Other names

28 names

Resolves to: a globoside Gb4Cer (d18:1(4E))

Also called: (Gal)2 (GalNAc)1 (Glc)1 (Cer)1beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(11')-Cerbeta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp-(11')-CerCTH/Gb4GalNAc-1->3-Gal-1->4-Gal-1->4-Glc-CerGalNAc-1→3-Gal-1→4-Gal-1→4-Glc-CerGalNAcbeta1-3-Galalpha1-4Galbeta1-4Glcbeta1-1CerGalNAcbeta1-3Galalpha1-4Galbeta1-4Glcbeta-CerGalNAcβ1-3-Galα1-4Galβ1-4Glcβ1-1CerGb4 GlobosideGb4 Globotetraosyl ceramideGb4CerGbose4CerGloboside Gb4Cer (d18:1(4E))Globoside GL-4Globoside IGloboside I/Cytolipin KGlobotetraosyl ceramideN-acetyl-D-galactosaminyl-(1->3)-D-galactosyl-(1->4)-D-galactosyl-(1->4)-D-glucosylceramidesN-acetyl-D-galactosaminyl-(1→3)-D-galactosyl-(1→4)-D-galactosyl-(1→4)-D-glucosylceramidesN-Acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramideN-Acetyl-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramideSlt-iiv receptorVT2vp1 Receptorβ-D-GalNAc-(1→3)-α-D-Gal-(1→4)-β-D-Gal-(1→4)-β-D-Glc-(1↔1')-Cerβ-D-GalpNAc-(1→3)-α-D-Galp-(1→4)-β-D-Galp-(1→4)-β-D-Glcp-(1↔1')-Cer
Systematic name: N-[(2S,3R,4E)-1-{[2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1->3)-alpha-D-galactopyranosyl-(1->4)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]oxy}-3-hydroxyoctadec-4-en-2-yl]alkanamideN-[(2S,3R,4E)-1-{[2-acetamido-2-deoxy-β-D-galactopyranosyl-(1→3)-α-D-galactopyranosyl-(1→4)-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]oxy}-3-hydroxyoctadec-4-en-2-yl]alkanamide