Loading the page.
Proteins/UNIPROT:Q9NS00
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development (By similarity)..
Function from UniProtKB (Q9NS00), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
68 statements
68 statements · 8 reference databases · Subject: C1GALT1 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
4 reactions
MAM03000g+CHEBI:67119proton+MAM02960g+UDP
Catalysed by C1GALT1 or C1GALT1C1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.122Golgi apparatus
Human-GEM MAR07438CC BY 4.0Reference data
an N-acetyl-alpha-D-galactosaminyl derivative+UDP-alpha-D-galactosea beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative+UDP+hydron
6 names
Resolves to: C1GALT1
Catalysed by C1GALT1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:15621CC BY 4.0Reference data
a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein]+UDP-alpha-D-galactosea 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein]+UDP+hydron
Catalysed by C1GALT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:56196CC BY 4.0Reference data
a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein]+UDP-alpha-D-galactosea 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein]+UDP+hydron
Catalysed by C1GALT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:56200CC BY 4.0Reference data