Compound
D-glucosyl-N-acylsphingosine
Cerebrosides which contain as their polar head group a glucose moiety bound in glycosidic linkage to the hydroxyl group of ceramides. Their accumulation in tissue, due to a defect in beta-glucosidase, is the cause of Gaucher's disease.
What it touches on the way
Mechanistic reach
37 entities
37 entities reached.
0 reported hops37 assembled from the scaffold
- CERT1ProteinUNIPROT:Q9Y5P4transported byInferred only94 paths47 endpoints
- B4GALT1ProteinUNIPROT:P15291substrate ofInferred only76 paths38 endpoints
- B3GNT3ProteinUNIPROT:Q9Y2A9substrate ofInferred only42 paths14 endpoints
- GLB1ProteinUNIPROT:P16278substrate ofInferred only38 paths38 endpoints
- B4GALT6ProteinUNIPROT:Q9UBX8substrate ofInferred only38 paths19 endpoints
- STT3AProteinUNIPROT:P46977substrate ofInferred only37 paths37 endpoints
- B4GALT5ProteinUNIPROT:O43286substrate ofInferred only34 paths18 endpoints
- GBA1ProteinUNIPROT:P04062substrate ofInferred only28 paths14 endpoints
- STT3BProteinUNIPROT:Q8TCJ2substrate ofInferred only26 paths26 endpoints
- B4GALT7ProteinUNIPROT:Q9UBV7substrate ofInferred only24 paths12 endpoints
- B4GALT2ProteinUNIPROT:O60909substrate ofInferred only23 paths12 endpoints
- B4GALT3ProteinUNIPROT:O60512substrate ofInferred only22 paths11 endpoints
Show the remaining 25
- B4GALT4ProteinUNIPROT:O60513substrate ofInferred only20 paths10 endpoints
- B3GALT1ProteinUNIPROT:Q9Y5Z6substrate ofInferred only18 paths9 endpoints
- B3GALT2ProteinUNIPROT:O43825substrate ofInferred only16 paths8 endpoints
- B3GNT5ProteinUNIPROT:Q9BYG0substrate ofInferred only15 paths15 endpoints
- GBA2ProteinUNIPROT:Q9HCG7substrate ofInferred only14 paths7 endpoints
- B4GALNT2ProteinUNIPROT:Q8NHY0substrate ofInferred only14 paths7 endpoints
- GLB1LProteinUNIPROT:Q6UWU2substrate ofInferred only11 paths11 endpoints
- B3GNT7ProteinUNIPROT:Q8NFL0substrate ofInferred only10 paths10 endpoints
- B3GALT5ProteinUNIPROT:Q9Y2C3substrate ofInferred only10 paths5 endpoints
- B3GLCTProteinUNIPROT:Q6Y288substrate ofInferred only9 paths9 endpoints
- B3GNT4ProteinUNIPROT:Q9C0J1substrate ofInferred only9 paths9 endpoints
- B3GNT9ProteinUNIPROT:Q6UX72substrate ofInferred only8 paths4 endpoints
- GCNT7ProteinUNIPROT:Q6ZNI0substrate ofInferred only8 paths4 endpoints
- A4GNTProteinUNIPROT:Q9UNA3substrate ofInferred only8 paths4 endpoints
- LCTProteinUNIPROT:P09848substrate ofInferred only8 paths8 endpoints
- FUT4ProteinUNIPROT:P22083substrate ofInferred only7 paths7 endpoints
- GALNT7ProteinUNIPROT:Q86SF2substrate ofInferred only7 paths7 endpoints
- POFUT4ProteinUNIPROT:Q495W5substrate ofInferred only6 paths3 endpoints
- PIGMProteinUNIPROT:Q9H3S5substrate ofInferred only6 paths6 endpoints
- PIGVProteinUNIPROT:Q9NUD9substrate ofInferred only6 paths6 endpoints
- PIGZProteinUNIPROT:Q86VD9substrate ofInferred only5 paths5 endpoints
- GBA3ProteinUNIPROT:Q9H227substrate ofInferred only5 paths5 endpoints
- B3GALNT2ProteinUNIPROT:Q8NCR0substrate ofInferred only5 paths5 endpoints
- FUT9ProteinUNIPROT:Q9Y231substrate ofInferred only5 paths5 endpoints
- B3GNT8ProteinUNIPROT:Q7Z7M8substrate ofInferred only4 paths4 endpoints
What the reference databases state
Statements
72 statements
72 statements · 1 reference database · Subject: D-glucosyl-N-acylsphingosine · Sources: Human-GEM
- D-glucosyl-N-acylsphingosine is a substrate of A4GNTProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of A4GNTProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of ALG1L2ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of ALG1L2ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GALNT2ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GALT1ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GALT1ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GALT2ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GALT2ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GALT5ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GALT5ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GLCTProteinHuman-GEM MAR00765Inferred only
Show the remaining 60
- D-glucosyl-N-acylsphingosine is a substrate of B3GNT3ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GNT3ProteinHuman-GEM MAR08147Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GNT3ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GNT4ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GNT5ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GNT7ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GNT8ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GNT9ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B3GNT9ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALNT2ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALNT2ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALNT3ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALNT4ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALNT4ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT1ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT1ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT2ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT2ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT3ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT3ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT4ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT4ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT5ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT5ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT6ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT6ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT7ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of B4GALT7ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of FUT4ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of FUT9ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GALNT7ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GBA1ProteinHuman-GEM MAR00762Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GBA1ProteinHuman-GEM MAR00787Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GBA2ProteinHuman-GEM MAR12050Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GBA2ProteinHuman-GEM MAR00762Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GBA3ProteinHuman-GEM MAR00762Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GBGT1ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GBGT1ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GCNT7ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GCNT7ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GLB1ProteinHuman-GEM MAR00766Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GLB1LProteinHuman-GEM MAR00766Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GLT6D1ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GLT6D1ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GLT8D1ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GLT8D1ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GLT8D2ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of GLT8D2ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of LCTProteinHuman-GEM MAR00766Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of PIGMProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of PIGVProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of PIGZProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of POFUT4ProteinHuman-GEM MAR00926Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of POFUT4ProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of SAPCD1ProteinHuman-GEM MAR00787Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of STT3AProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is a substrate of STT3BProteinHuman-GEM MAR00765Inferred only
- D-glucosyl-N-acylsphingosine is transported by CERT1ProteinHuman-GEM MAR08146Inferred only
- D-glucosyl-N-acylsphingosine is transported by CERT1ProteinHuman-GEM MAR00768Inferred only
- D-glucosyl-N-acylsphingosine is transported by GLTPProteinHuman-GEM MAR00770Inferred only
Reactions
19 reactions
an N-acylsphing-4-enine+MAM03108cD-glucosyl-N-acylsphingosine+proton+UDP
Catalysed by UGCG
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.80cytosol
Human-GEM MAR00761CC BY 4.0Reference data
D-glucosyl-N-acylsphingosine+wateran N-acylsphing-4-enine+D-glucose
Catalysed by GBA2 or GBA1 or GBA3
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.45cytosol
Human-GEM MAR00762CC BY 4.0Reference data
D-glucosyl-N-acylsphingosine+CHEBI:67119proton+a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))+UDP
Catalysed by GLT8D1 or B4GALT7 or PIGV or B4GALT1 or GALNT7 or B4GALT2 or A4GNT or B4GALT6 or PIGZ or GLT8D2 or B4GALT4 or GCNT7 and 23 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-endoplasmic reticulum
Human-GEM MAR00765CC BY 4.0Reference data
alpha-D-galactose+D-glucosyl-N-acylsphingosinewater+a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))
Catalysed by LCT or GLB1L or GLB1
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.23extracellular space
Human-GEM MAR00766CC BY 4.0Reference data
D-glucosyl-N-acylsphingosineD-glucosyl-N-acylsphingosine
Transported by CERT1
Reaction pageLeft to rightBalance undeterminablecytosol, endoplasmic reticulum
Human-GEM MAR00768CC BY 4.0Reference data
D-glucosyl-N-acylsphingosineD-glucosyl-N-acylsphingosine
Reaction pageReversibleBalance undeterminablecytosol, lysosome
Human-GEM MAR00769CC BY 4.0Reference data
D-glucosyl-N-acylsphingosineD-glucosyl-N-acylsphingosine
Transported by GLTP
Reaction pageReversibleBalance undeterminablecytosol, extracellular space
Human-GEM MAR00770CC BY 4.0Reference data
water+a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))alpha-D-galactose+D-glucosyl-N-acylsphingosine
Catalysed by LCT & GLB1 & GLB1L & TMPPE
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.23lysosome
Human-GEM MAR00786CC BY 4.0Reference data
D-glucosyl-N-acylsphingosine+wateran N-acylsphing-4-enine+D-glucose
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.45lysosome
Human-GEM MAR00787CC BY 4.0Reference data
D-glucosyl-N-acylsphingosine+CHEBI:67119proton+a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))+UDP
Catalysed by GLT8D1 or B4GALT7 or B4GALT1 or B4GALT2 or A4GNT or B4GALT6 or GLT8D2 or B4GALT4 or GCNT7 or GBGT1 or B4GALT5 or B4GALT3 and 12 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-cytosol
Human-GEM MAR00926CC BY 4.0Reference data
D-glucosyl-N-acylsphingosineD-glucosyl-N-acylsphingosine
Transported by CERT1
Reaction pageReversibleBalance undeterminablecytosol, Golgi apparatus
Human-GEM MAR08146CC BY 4.0Reference data
D-glucosyl-N-acylsphingosine+CHEBI:67119proton+a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))+UDP
Catalysed by B3GNT3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.-Golgi apparatus
Human-GEM MAR08147CC BY 4.0Reference data
On the label
Labelled products
1 product
Source: NIH DSLD · Ingredient: D-glucosyl-N-acylsphingosine · 1 product · Declared amount per serving: Not stated
0 labels state an amount1 does not
- DEVAVegan Ceramide Supplementamount not statedper 1 Capsule(s)DSLD:276492
Label record: NIH Office of Dietary Supplements · CC0
Where it reaches
8 systems, 19 regions, 42 tissues, 42 transporter routes — routes, not measurements: transporters known to carry D-glucosyl-N-acylsphingosine are expressed there, and no source reports it arriving.
Loading the model…
Other names
3 names
Resolves to: D-glucosyl-N-acylsphingosine
- Also called
- GlucocerebrosideGlucosylceramideN-acyl-D-glucosylsphingosine