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Proteins/UNIPROT:P54803
Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon..
Function from UniProtKB (P54803), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
123 statements
123 statements · 6 reference databases · Subject: GALC · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
6 reactions
CHEBI:12947+wateran N-acylsphing-4-enine+D-glucose
Catalysed by GALC
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.46lysosome
Human-GEM MAR00793CC BY 4.0Reference data
water+psychosinealpha-D-galactose+sphing-4-enine
Catalysed by GALC
Reaction pageLeft to rightBalancedEC 3.2.1.46lysosome
4 names
Resolves to: GALC
CHEBI:12947+wateran N-acylsphing-4-enine+alpha-D-galactose
Catalysed by GALC
Reaction pageLeft to rightBalance undeterminableEC 3.2.1.46lysosome
Human-GEM MAR08210CC BY 4.0Reference data
a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine+waterD-galactose+an N-acylsphing-4-enine
Catalysed by GBA1 or GALC or GBA3 or GBA2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:14297CC BY 4.0Reference data
a D-galactosylceramide+wateran N-acyl-sphingoid base+D-galactose
Catalysed by GALC
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:43412CC BY 4.0Reference data
beta-D-galactosyl-(1<->1)-sphing-4-enine+watersphing-4-enine+D-galactose
Reaction pageLeft to rightBalanced
Rhea RHEA:43908CC BY 4.0Reference data