aldehydo-N-acetyl-D-mannosamine

1. aceneuramate = aldehydo-N-acetyl-D-mannosamine + pyruvate

Catalysed by NPL

1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)

Catalysed by NPLcytosol

1. N-acetyl-D-glucosamine 2-epimerase

Catalysed by RENBPcytosol

1. ATP:N-acyl-D-mannosamine 6-phosphotransferase

Catalysed by GNEcytosolOne of 2 routes

1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
2. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)

Catalysed by NPLcytosolOne of 2 routes

1. ATP:N-acyl-D-mannosamine 6-phosphotransferase
2. N-acetylneuraminate synthase

Catalysed by GNE, NANScytosolOne of 2 routes

1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
2. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
3. transport of 2-hydroxybutyrate and pyruvate (cytosol to extracellular)

Catalysed by NPL, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

1. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
2. CTP:N-acetylneuraminate cytidylyltransferase
3. a beta-D-galactoside + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivative + CMP + H(+)