S-adenosyl 3-(methylsulfanyl)propylamine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

137 compounds within 3 steps: 3 in 1, 14 in 2, 120 in 3

One step

S-methyl-5'-thioadenosineReach from here →
1. S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+)
Catalysed by SRMOne of 2 routes
spermineReach from here →
1. S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = spermine + S-methyl-5'-thioadenosine + H(+)
Catalysed by SMS
spermidineReach from here →
1. S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+)
Catalysed by SRM

Two steps

CHEBI:1146900Reach from here →
1. S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+)
2. diamine N-acetyltransferase (N1-acetylspermidine)
Catalysed by SRM, SAT1, SAT2cytosolOne of 3 routes
trimethylenediamineReach from here →
1. S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+)
2. deoxyhypusine synthase (1,3-diaminopropane)
Catalysed by SRM, DHPScytosolOne of 2 routes
CHEBI:15746

Three steps

Reach from here →

Catalysed by SRM, SMScytosol

adenineReach from here →

Catalysed by SRM, MTAPcytosolOne of 2 routes

CHEBI:17769Reach from here →

Catalysed by SRMcytosol

CHEBI:17927Reach from here →

Catalysed by SRM, SAT1, SAT2cytosolOne of 2 routes

N-(4-aminobutyl)-3-aminopropanalReach from here →

Catalysed by SRM, AOC2, AOC1, AOC3cytosolOne of 3 routes

putrescineReach from here →

Catalysed by SRMOne of 2 routes

propane-1,3-diamineReach from here →

Catalysed by SRM, DHPS

N(1)-acetylspermineReach from here →

Catalysed by SRM, PAOXOne of 2 routes

N(1)-acetylspermidineReach from here →

Catalysed by SRM, SAT1

3-aminopropanalReach from here →

Catalysed by SMS, SMOX

5-(methylsulfanyl)-alpha-D-ribose 1-phosphateReach from here →

Catalysed by SRM, MTAPcytosolOne of 2 routes

N(8)-acetylspermidineReach from here →

Catalysed by SRMcytosolOne of 3 routes

Catalysed by SRM, SAT1, SAT2, CPT1A and 2 morecytosolOne of 3 routes

CHEBI:15345Reach from here →

Catalysed by SRM, SAT1, SAT2, AACScytosolOne of 2 routes

cholineReach from here →

Catalysed by SRM, SAT1, SAT2, CHATcytosol, nucleus

CHEBI:15380Reach from here →

Catalysed by SRM, SAT1, SAT2, ALAS1 and 1 morecytosol, mitochondrial matrixOne of 8 routes

CHEBI:15477Reach from here →

Catalysed by SRM, SAT1, SAT2, GLYAT and 2 morecytosol, mitochondrial matrixOne of 2 routes

2-methylcrotonoyl-CoAReach from here →

Catalysed by SRM, SAT1, SAT2, CPT1A and 1 morecytosolOne of 2 routes

isobutyryl-CoAReach from here →

Catalysed by SRM, SAT1, SAT2, HADHA and 2 morecytosol, mitochondrial matrixOne of 3 routes

3-methylbut-2-enoyl-CoAReach from here →

Catalysed by SRM, SAT1, SAT2, GLYATcytosol, mitochondrial matrix

isovaleryl-CoAReach from here →

Catalysed by SRM, SAT1, SAT2, GLYAT and 2 morecytosol, mitochondrial matrixOne of 3 routes

arachidonoyl-CoAReach from here →

Catalysed by SRM, SAT1, SAT2, SLC27A2 and 7 morecytosolOne of 11 routes

CHEBI:15519Reach from here →

Catalysed by SRM, SAT1, SAT2, ACAA1 and 2 morecytosol, peroxisomeOne of 2 routes

palmitoyl-CoAReach from here →

Catalysed by SRM, SAT1, SAT2, SLC27A2 and 7 morecytosolOne of 11 routes

oleoyl-CoAReach from here →

Catalysed by SRM, SAT1, SAT2, CPT1A and 2 morecytosolOne of 11 routes

phenylacetyl-CoAReach from here →

Catalysed by SRM, SAT1, SAT2cytosolOne of 3 routes

propionyl-CoAReach from here →

Catalysed by SRM, SAT1, SAT2, ACSS3 and 2 morecytosolOne of 43 routes

CHEBI:15650Reach from here →

Catalysed by SRM, SAT1, SAT2, ZDHHC11B and 31 morecytosolOne of 2 routes

CHEBI:15727Reach from here →

Catalysed by SRM, SAT1, SAT2, NAA10cytosol

11-cis-retinolReach from here →

Catalysed by SRM, SAT1, SAT2, DGAT1 and 4 morecytosol

adenosineReach from here →

Catalysed by SRM, MTAP, PNPcytosol

oxaloacetateReach from here →

Catalysed by SRM, SAT1, SAT2, ACLYcytosol

L-arginineReach from here →

Catalysed by SRM, SLC3A2, SLC7A7extracellular space, cytosolOne of 2 routes

2'-deoxyadenosineReach from here →

Catalysed by SRM, MTAP, PNPcytosol

anilineReach from here →

Catalysed by SRM, SAT1, SAT2, NAT2 and 1 morecytosol

CHEBI:17312Reach from here →

Catalysed by SRM, SMS, SAT1, SAT2cytosolOne of 4 routes

hypoxanthineReach from here →

Catalysed by SRM, MTAPcytosol

L-cysteineReach from here →

Catalysed by SRM, SAT1, SAT2, NAGScytosol, mitochondrial matrix

(7Z,10Z,13Z)-hexadecatrienoyl-CoAReach from here →

Catalysed by SRM, SAT1, SAT2, HADHA and 2 morecytosol, mitochondrial matrix

CHEBI:18019Reach from here →

Catalysed by SRM, DHPScytosol

spermine monoaldehydeReach from here →

Catalysed by SRM, SMS, AOC2, AOC1 and 1 morecytosolOne of 3 routes

(5Z)-dodecenoyl-CoAReach from here →

Catalysed by SRM, SAT1, SAT2, HADHA and 2 morecytosol, mitochondrial matrixOne of 2 routes

(11Z)-docosenoyl-CoA(4-)Reach from here →

Catalysed by SRM, SAT1, SAT2, SLC27A2 and 7 morecytosolOne of 5 routes

(7Z)-tetradecenoyl-CoAReach from here →

Catalysed by SRM, SAT1, SAT2, SLC27A2 and 7 morecytosolOne of 8 routes