Structure
No depiction stored
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- Class
- Organic compound
- Formula
- C5H5N5
- Mass
- 135.13 g/mol
- Charge
- 0
- InChIKey
- GFFGJBXGBJISGV-UHFFFAOYSA-N
- SMILES
- Nc1ncnc2ncnc12
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
6 entities
6 entities reached.
0 reported hops6 assembled from the scaffold
- PNPProteinUNIPROT:P00491substrate ofInferred only72 paths36 endpoints
- APRTProteinUNIPROT:P07741substrate ofInferred only66 paths22 endpoints
- SLC29A1ProteinUNIPROT:Q99808transported byInferred only43 paths43 endpoints
- SLC43A3ProteinUNIPROT:Q8NBI5transported byInferred only8 paths8 endpoints
- AQP9ProteinUNIPROT:O43315transported byInferred only8 paths7 endpoints
- SLC29A2ProteinUNIPROT:Q14542transported byInferred only6 paths3 endpoints
What the reference databases state
Chemical structure
- adenosine has the functional parent adenineCompoundChEBI CHEBI:16335Inferred only
- hypoxanthine has the functional parent adenineCompoundChEBI CHEBI:17368Inferred only
Statements
14 statements
14 statements · 2 reference databases · Subject: adenine · Sources: Human-GEM, Rhea
- hypoxanthine is converted to adenineCompoundRhea RHEA:23688Inferred only
- adenine is converted to hypoxanthineCompoundHuman-GEM MAR09797Inferred only
- adenine is converted to hypoxanthineCompoundRhea RHEA:23688Inferred only
- adenine is a substrate of APRTProteinHuman-GEM MAR04086Inferred only
- adenine is a substrate of APRTProteinRhea RHEA:16609Inferred only
- adenine is a substrate of APRTProteinHuman-GEM MAR04085Inferred only
- adenine is a substrate of PNPProteinHuman-GEM MAR04695Inferred only
- adenine is a substrate of PNPProteinHuman-GEM MAR08486Inferred only
- adenine is transported by AQP9ProteinRhea RHEA:71523Inferred only
- adenine is transported by SLC29A1ProteinRhea RHEA:71523Inferred only
- adenine is transported by SLC29A2ProteinRhea RHEA:71523Inferred only
- adenine is transported by SLC29A2ProteinHuman-GEM MAR04847Inferred only
Show the remaining 2
- adenine is transported by SLC29A3ProteinHuman-GEM MAR07710Inferred only
- adenine is transported by SLC43A3ProteinRhea RHEA:71523Inferred only
Reactions
32 reactions
adenine+5-phospho-alpha-D-ribose 1-diphosphateAMP+diphosphate(3-)
Catalysed by APRT
Reaction pageLeft to rightBalancedEC 2.4.2.7cytosol
Human-GEM MAR04085CC BY 4.0Reference data
adenine+5-phospho-alpha-D-ribose 1-diphosphateAMP+diphosphate(3-)
Catalysed by APRT
Reaction pageLeft to rightBalancedEC 2.4.2.7extracellular space
Human-GEM MAR04086CC BY 4.0Reference data
MAM00639c+adenine2'-deoxyadenosine+phosphate(3-)
Catalysed by PNP
Reaction pageReversibleBalancedEC 2.4.2.1, 2.4.2.4cytosol
Human-GEM MAR04695CC BY 4.0Reference data
Transported by SLC29A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR04847CC BY 4.0Reference data
S-methyl-5'-thioadenosine+phosphate(3-)adenine+5-(methylsulfanyl)-alpha-D-ribose 1-phosphate
Catalysed by MTAP
Reaction pageLeft to rightBalancedEC 2.4.2.28cytosol
Human-GEM MAR05384CC BY 4.0Reference data
Transported by SLC29A3
Reaction pageReversibleBalancedcytosol, lysosome
Human-GEM MAR07710CC BY 4.0Reference data
adenosine+phosphate(3-)adenine+D-ribose 1-phosphate
Catalysed by PNP
Reaction pageReversibleBalancedEC 2.4.2.1cytosol
Human-GEM MAR08486CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09253CC BY 4.0Reference data
adenine+waterhypoxanthine+ammonium
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR09797CC BY 4.0Reference data
S-methyl-5'-thioadenosine+hydrogenphosphate5-(methylsulfanyl)-alpha-D-ribose 1-phosphate+adenine
Reaction pageLeft to rightBalanced
Rhea RHEA:11852CC BY 4.0Reference data
S-methyl-5'-thioadenosine+waterCHEBI:78440+adenine
Reaction pageDirection not assertedBalanced
Rhea RHEA:13617CC BY 4.0Reference data
CHEBI:17660+A+waterCHEBI:15825+adenine+AH2
Reaction pageDirection not assertedBalanced
Rhea RHEA:13625CC BY 4.0Reference data
Where it reaches
7 systems, 17 regions, 51 tissues, 58 transporter routes — routes, not measurements: transporters known to carry adenine are expressed there, and no source reports it arriving.
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Other names
4 names
Resolves to: adenine
- Also called
- 6-AminopurineAdeAdenin
- Systematic name
- 9H-purin-6-amine