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Proteins/UNIPROT:O75106
Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Has a preference for 2-phenylethylamine, tryptamine and tyramine. Could also act on methylamine and benzylamine but much less efficiently..
Function from UniProtKB (O75106), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
45 statements
45 statements · 5 reference databases · Subject: AOC2 · Sources: Hetionet, Human-GEM, Reactome, Rhea, UniProt
32 reactions
water+dioxygen+putrescineCHEBI:17769+proton+hydrogen peroxide+ammonium
Catalysed by AOC1 or AOC3 or AOC2
Reaction pageLeft to rightBalancedEC 1.4.3.10, 1.4.3.21, 1.4.3.22extracellular space
Human-GEM MAR04423CC BY 4.0Reference data
5 names
Resolves to: AOC2
Reaction pageLeft to rightBalancedEC 1.4.3.4cytosol
Human-GEM MAR04430CC BY 4.0Reference data
water+dioxygen+2-phenylethylamineproton+hydrogen peroxide+ammonium+2-phenylacetaldehyde
Catalysed by AOC1 or MAOB or AOC3 or AOC2 or MAOA
Reaction pageLeft to rightBalancedEC 1.4.3.4, 1.4.3.21cytosol
Human-GEM MAR04682CC BY 4.0Reference data
dopamine+water+dioxygen3,4-dihydroxyphenylacetaldehyde+proton+hydrogen peroxide+ammonium
Catalysed by AOC1 or MAOB or AOC3 or AOC2 or MAOA
Reaction pageLeft to rightBalancedEC 1.4.3.4, 1.4.3.21, 1.4.3.22cytosol
Human-GEM MAR06758CC BY 4.0Reference data
water+dioxygen+MAM03099cMAM01002c+proton+hydrogen peroxide+ammonium
Catalysed by AOC1 or MAOB or AOC3 or AOC2 or MAOA
Reaction pageLeft to rightBalancedEC 1.4.3.4, 1.4.3.21cytosol
Human-GEM MAR06789CC BY 4.0Reference data
water+dioxygen+CHEBI:15746proton+hydrogen peroxide+ammonium+spermine monoaldehyde
Catalysed by AOC1 or AOC3 or AOC2
Reaction pageLeft to rightBalancedEC 1.4.3.21, 1.4.3.22cytosol
Human-GEM MAR06931CC BY 4.0Reference data
water+dioxygen+CHEBI:15746proton+hydrogen peroxide+ammonium+spermine monoaldehyde
Catalysed by AOC1 or AOC3 or AOC2
Reaction pageLeft to rightBalancedEC 1.4.3.21, 1.4.3.22extracellular space
Human-GEM MAR06932CC BY 4.0Reference data
FAD+water+CHEBI:15746FADH2+proton+ammonium+spermine monoaldehyde
Catalysed by AOC1 or AOC3 or AOC2
Reaction pageLeft to rightBalancedEC 1.4.3.21, 1.4.3.22peroxisome
Human-GEM MAR06933CC BY 4.0Reference data
water+dioxygen+spermine monoaldehydeproton+hydrogen peroxide+ammonium+MAM02924c
Catalysed by AOC1 or AOC3 or AOC2
Reaction pageLeft to rightBalancedEC 1.4.3.21, 1.4.3.22cytosol
Human-GEM MAR06934CC BY 4.0Reference data
water+dioxygen+spermine monoaldehydeproton+hydrogen peroxide+ammonium+MAM02924e
Catalysed by AOC1 or AOC3 or AOC2
Reaction pageLeft to rightBalancedEC 1.4.3.21, 1.4.3.22extracellular space
Human-GEM MAR06935CC BY 4.0Reference data
FAD+water+spermine monoaldehydeFADH2+proton+ammonium+MAM02924x
Catalysed by AOC1 or AOC3 or AOC2
Reaction pageLeft to rightBalancedEC 1.4.3.21, 1.4.3.22peroxisome
Human-GEM MAR06936CC BY 4.0Reference data
water+dioxygen+spermidineproton+hydrogen peroxide+ammonium+N-(4-aminobutyl)-3-aminopropanal
Catalysed by AOC1 or AOC3 or AOC2
Reaction pageLeft to rightBalancedEC 1.4.3.21, 1.4.3.22cytosol
Human-GEM MAR06941CC BY 4.0Reference data