hypoxanthine

1. IMP:diphosphate phospho-D-ribosyltransferase

Catalysed by HPRT1cytosol

1. inosine:phosphate alpha-D-ribosyltransferase

Catalysed by PNPcytosol

1. hypoxanthine:NAD+ oxidoreductase

Catalysed by XDHcytosolOne of 4 routes

1. Deoxyinosine:orthophosphate ribosyltransferase

Catalysed by PNPcytosolOne of 2 routes

1. IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate

Catalysed by HPRT1

1. inosine:phosphate alpha-D-ribosyltransferase
2. transport of adenosine and inosine (cytosol to extracellular)

Catalysed by PNPcytosol, extracellular spaceOne of 3 routes

1. inosine:phosphate alpha-D-ribosyltransferase
2. inosine + UMP = uridine + IMP

Catalysed by PNP, NT5C2cytosol

1. IMP:diphosphate phospho-D-ribosyltransferase
2. IMP 1,2-hydrolase (decyclizing)
3. phosphoribosylaminoimidazolecarboxamide formyltransferase (10-formyl-THF)

Catalysed by HPRT1, ATICcytosol

1. inosine:phosphate alpha-D-ribosyltransferase
2. inosine:phosphate alpha-D-ribosyltransferase
3. purine nucleoside phosphorylase (nicotinamide)

Catalysed by PNPcytosol