propane-1,3-diamine

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine

Catalysed by DHPS

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. diamine N-acetyltransferase (N1-acetylspermidine)

Catalysed by DHPS, SAT1, SAT2cytosolOne of 3 routes

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. deoxyhypusine synthase (1,3-diaminopropane)

Catalysed by DHPScytosolOne of 2 routes

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. S-adenosylmethioninamine:spermidine 3-aminopropyltransferase

Catalysed by DHPS, SRM, SMScytosol

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. S-adenosylmethioninamine:spermidine 3-aminopropyltransferase

Catalysed by DHPS, SRM, SMScytosolOne of 2 routes

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. spermidine:(acceptor) oxidoreductase

Catalysed by DHPScytosol

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. diamine N-acetyltransferase (N1-acetylspermidine)

Catalysed by DHPS, SAT1, SAT2cytosolOne of 2 routes

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. primary-amine oxidase (spermidine)

Catalysed by DHPS, AOC2, AOC1, AOC3cytosolOne of 3 routes

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+)

Catalysed by DHPS, SRM

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = spermine + S-methyl-5'-thioadenosine + H(+)

Catalysed by DHPS, SMSOne of 2 routes

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+)

Catalysed by DHPS, SRM

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2

Catalysed by DHPS, PAOX

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. spermidine + acetyl-CoA = N(1)-acetylspermidine + CoA + H(+)

Catalysed by DHPS, SAT1

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. N8-acetylspermidine to spermidine conversion

Catalysed by DHPScytosolOne of 3 routes

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. diamine N-acetyltransferase (N1-acetylspermidine)
3. Carnitine O-Palmitoyltransferase

Catalysed by DHPS, SAT1, SAT2, CPT1A and 2 morecytosolOne of 244 routes

1. [eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine
2. diamine N-acetyltransferase (N1-acetylspermidine)
3. carnitine O-palmitoyltransferase ((7Z)-octadecenoyl-CoA)