N-(acetyl)-sphing-4-enine

Two steps

• sn-glycero-3-phosphoethanolamineReach from here →
  1. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
  2. 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine

  Catalysed by PLA2G15, PLA2G4COne of 6 routes

• cholineReach from here →
  1. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
  2. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + choline + H(+)

  Catalysed by PLA2G15, ENPP2, GDPD1One of 5 routes

• acetylpyruvateReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. acetylpyruvate + H2O = acetate + pyruvate + H(+)

  Catalysed by ASAH1, FAHD1

• pyruvateReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. transport of acetate and pyruvate (cytosol to extracellular)

  Catalysed by ASAH1, SLC16A4, SLC16A5, SLC16A3 and 2 moreextracellular space, cytosolOne of 2 routes

• all-trans-retinoic acidReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. transport of acetate and retinoate (cytosol to extracellular)

  Catalysed by ASAH1, SLC16A4, SLC16A5, SLC16A7extracellular space, cytosolOne of 2 routes

• a sterolReach from here →
  1. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
  2. a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine

  Catalysed by PLA2G15, LCAT

• N(2)-acetyl-L-ornithineReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. N2-Acetyl-L-ornithine amidohydrolase

  Catalysed by ASAH1, ACY1cytosol

• sn-glycerol 3-phosphocholineReach from here →
  1. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
  2. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)

  Catalysed by PLA2G15, PNPLA7, ASPG, PNPLA6One of 20 routes

• psychosineReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. UDP-alpha-D-galactose:sphingosine 1-beta-galactosyltransferase

  Catalysed by ASAH1cytosol

• (R)-3-hydroxybutyric acidReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. transport of (R)-3-hydroxybutanoate and acetate (cytosol to extracellular)

  Catalysed by ASAH1, SLC16A4, SLC16A5, SLC16A7 and 1 moreextracellular space, cytosolOne of 2 routes

• 17alpha-hydroxyprogesteroneReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. cytochrome P450 (17alpha-hydroxyprogesterone)

  Catalysed by ASAH1, CYP17A1endoplasmic reticulum

• 4-methylumbelliferyl acetateReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)

  Catalysed by ASAH1, CES2, ESD, CES1

• 1-octadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphoethanolamine
  2. a 2-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-octadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA

  Catalysed by PLA2G15, LPGAT1

• 1-acyl-sn-glycero-3-phospho-(3'-acyl-sn-1'-glycerol)Reach from here →
  1. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)
  2. 2 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) = 1-acyl-sn-glycero-3-phospho-(3'-acyl-sn-1'-glycerol) + sn-glycero-3-phospho-(1'-sn-glycerol)

  Catalysed by PLA2G15, CLN5

• 1-octadecanoyl-sn-glycero-3-phospho-(3'-octadecanoyl-1'-sn-glycerol)Reach from here →
  1. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
  2. 2 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) = 1-octadecanoyl-sn-glycero-3-phospho-(3'-octadecanoyl-1'-sn-glycerol) + sn-glycero-3-phospho-(1'-sn-glycerol)

  Catalysed by PLA2G15, CLN5

• octadecanoateReach from here →
  1. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
  2. 1-octadecanoyl-sn-glycero-3-phosphocholine + H2O = octadecanoate + sn-glycerol 3-phosphocholine + H(+)

  Catalysed by PLA2G15, LYPLA2, ASPGOne of 2 routes

• 17alpha-hydroxypregnenoloneReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. cytochrome P450 (17alpha-hydroxypregnenolone)

  Catalysed by ASAH1, CYP17A1endoplasmic reticulum

• a fatty acidReach from here →
  1. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
  2. a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)

  Catalysed by PLA2G15, PLA2G6, PLA2G4B, LIPC and 7 moreOne of 4 routes

• phosphocholineReach from here →
  1. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
  2. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + phosphocholine + H(+)

  Catalysed by PLA2G15, ENPP6, ABHD12One of 3 routes

• formic acidReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. transport of acetate and formate (cytosol to extracellular)

  Catalysed by ASAH1, SLC16A4, SLC16A5, SLC16A1extracellular space, cytosolOne of 2 routes

• propionic acidReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. transport of acetate and propanoate (cytosol to extracellular)

  Catalysed by ASAH1, SLC16A4, SLC16A5, SLC16A7 and 1 moreextracellular space, cytosolOne of 2 routes

• butyric acidReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. transport of acetate and butyrate (cytosol to extracellular)

  Catalysed by ASAH1, SLC16A4, SLC16A5, SLC16A7 and 1 moreextracellular space, cytosolOne of 2 routes

• (9Z)-octadecenoateReach from here →
  1. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
  2. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)

  Catalysed by PLA2G15, PNPLA7, ASPG, PNPLA6

• a 1-O-alkyl-sn-glycero-3-phosphocholineReach from here →
  1. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
  2. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine

  Catalysed by PLA2G15, LCAT

• (5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
  1. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine
  2. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

  Catalysed by PLA2G15, PLA2G6, ASPG

• sphingosine 1-phosphateReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. ATP:sphingosine 1-phosphotransferase

  Catalysed by ASAH1, DBP, SPHK2, SPHK1cytosolOne of 2 routes

• (S)-lactic acidReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. transport of acetate and L-lactate (cytosol to extracellular)

  Catalysed by ASAH1, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosolOne of 2 routes

• an N-acylsphing-4-enineReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. sphing-4-enine + a fatty acyl-CoA = an N-acylsphing-4-enine + CoA + H(+)

  Catalysed by ASAH1, CERS1, CERS6, CERS3 and 3 more

• a 1,2-diacyl-sn-glycero-3-phospho-L-serineReach from here →
  1. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phospho-L-serine
  2. a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA

  Catalysed by PLA2G15, LPCAT4, LPCAT3, MBOAT1

• N-acetyl-D-glucosamine 6-phosphateReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate

  Catalysed by ASAH1, AMDHD2

• 1-hexadecanoyl-sn-glycero-3-phosphateReach from here →
  1. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
  2. 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphate + choline + H(+)

  Catalysed by PLA2G15, ENPP2, GDPD3, GDPD1One of 2 routes

• ethanolamineReach from here →
  1. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine
  2. 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphate + ethanolamine + H(+)

  Catalysed by PLA2G15, GDPD1One of 2 routes

• a 1,2-diacyl-sn-glycero-3-phosphocholineReach from here →
  1. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
  2. a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA

  Catalysed by PLA2G15, PRDX6, LPCAT4, LPCAT3 and 4 moreOne of 6 routes

• a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
  1. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
  2. a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + a 1-acyl-sn-glycero-3-phosphocholine = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine

  Catalysed by PLA2G15, ASPG

• a 1-acyl-sn-glycero-3-phosphateReach from here →
  1. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
  2. a 1-acyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphate + choline + H(+)

  Catalysed by PLA2G15, ENPP2One of 4 routes

• N-acetylputrescineReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. N-acetylputrescine + H2O = putrescine + acetate

  Catalysed by ASAH1, HDAC10

• a 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholineReach from here →
  1. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
  2. a 1-acyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = a 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA

  Catalysed by PLA2G15, LPCAT4

• N(8)-acetylspermidineReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. N(8)-acetylspermidine + H2O = spermidine + acetate

  Catalysed by ASAH1, HDAC10

• an N-acetyl-L-cysteine-S-conjugateReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate

  Catalysed by ASAH1, ACY3

• 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholineReach from here →
  1. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
  2. (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA

  Catalysed by PLA2G15, LPCAT3

• sphing-4-enine 1-phosphateReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. sphing-4-enine + ATP = sphing-4-enine 1-phosphate + ADP + H(+)

  Catalysed by ASAH1, SPHK2, SPHK1

• 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
  1. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine
  2. 2 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine = 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine

  Catalysed by PLA2G15, ASPG

• 1-O-hexadecyl-sn-glycero-3-phosphocholineReach from here →
  1. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
  2. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-hexadecyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine + H(+)

  Catalysed by ASAH1, PAFAH2

• a 1,2-diacyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
  2. a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine = sn-glycerol 3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine

  Catalysed by PLA2G15, ASPGOne of 4 routes

• a 1-acyl-sn-glycerolReach from here →
  1. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
  2. a 1-acyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycerol + phosphocholine + H(+)

  Catalysed by PLA2G15, ENPP6

• a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
  1. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)
  2. 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA

  Catalysed by PLA2G15, LCLAT1, LPCAT1, GPAMOne of 2 routes

• sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
  1. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
  2. 2 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) = 1-octadecanoyl-sn-glycero-3-phospho-(3'-octadecanoyl-1'-sn-glycerol) + sn-glycero-3-phospho-(1'-sn-glycerol)

  Catalysed by PLA2G15, CLN5One of 2 routes

• 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerolReach from here →
  1. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
  2. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a cardiolipin + a 1-acyl-sn-glycero-3-phosphocholine

  Catalysed by PLA2G15, TAFAZZIN

• sn-glycero-3-phospho-L-serineReach from here →
  1. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phosphoserine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
  2. 1-octadecanoyl-sn-glycero-3-phosphoserine + H2O = sn-glycero-3-phospho-L-serine + octadecanoate + H(+)

  Catalysed by PLA2G15, ABHD12One of 2 routes

• a 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
  1. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
  2. a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + 1-hexadecanoyl-sn-glycero-3-phosphocholine = a 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine

  Catalysed by PLA2G15, ASPG