Compound
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)
The conjugate base of a 1-phosphatidyl-1D-myo-inositol; major species at pH 7.3.
Definition from ChEBI (CHEBI:57880), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Structural class, not a single molecule
- Formula
- C11H16O13PR2
- Mass
- 387.211 g/mol
- Charge
- -1
- SMILES
- *C(=O)OC[C@H](COP(=O)([O-])O[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O)OC(*)=O
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
30 entities
30 entities reached.
0 reported hops30 assembled from the scaffold
- PIK3CAProteinUNIPROT:P42336substrate ofInferred only260 paths260 endpoints
- PLCG1ProteinUNIPROT:P19174substrate ofInferred only221 paths221 endpoints
- VDAC2ProteinUNIPROT:P45880transported byInferred only166 paths137 endpoints
- CLPTM1LProteinUNIPROT:Q96KA5transported byInferred only110 paths110 endpoints
- PIK3CDProteinUNIPROT:O00329substrate ofInferred only110 paths110 endpoints
- PIK3CGProteinUNIPROT:P48736substrate ofInferred only84 paths84 endpoints
- PIK3C3ProteinUNIPROT:Q8NEB9substrate ofInferred only63 paths63 endpoints
- PLCB3ProteinUNIPROT:Q01970substrate ofInferred only59 paths59 endpoints
- PLCB1ProteinUNIPROT:Q9NQ66substrate ofInferred only56 paths56 endpoints
- PLCB2ProteinUNIPROT:Q00722substrate ofInferred only56 paths56 endpoints
- PITPNBProteinUNIPROT:P48739transported byInferred only54 paths54 endpoints
- PLTPProteinUNIPROT:P55058transported byInferred only44 paths44 endpoints
Show the remaining 18
- PLCB4ProteinUNIPROT:Q15147substrate ofInferred only31 paths31 endpoints
- PIK3C2AProteinUNIPROT:O00443substrate ofInferred only31 paths31 endpoints
- PITPNAProteinUNIPROT:Q00169transported byInferred only31 paths31 endpoints
- PIK3C2BProteinUNIPROT:O00750substrate ofInferred only24 paths24 endpoints
- PIK3C2GProteinUNIPROT:O75747substrate ofInferred only19 paths19 endpoints
- PLCD1ProteinUNIPROT:P51178substrate ofInferred only17 paths17 endpoints
- PI4KAProteinUNIPROT:P42356substrate ofInferred only15 paths15 endpoints
- CDIPTProteinUNIPROT:O14735substrate ofInferred only12 paths12 endpoints
- PI4K2AProteinUNIPROT:Q9BTU6substrate ofInferred only10 paths10 endpoints
- PI4KBProteinUNIPROT:Q9UBF8substrate ofInferred only10 paths10 endpoints
- PI4K2BProteinUNIPROT:Q8TCG2substrate ofInferred only9 paths9 endpoints
- PIKFYVEProteinUNIPROT:Q9Y2I7substrate ofInferred only9 paths9 endpoints
- PLCD4ProteinUNIPROT:Q9BRC7substrate ofInferred only8 paths8 endpoints
- PITPNM1ProteinUNIPROT:O00562transported byInferred only6 paths3 endpoints
- DDHD1ProteinUNIPROT:Q8NEL9substrate ofInferred only5 paths5 endpoints
- PIGAProteinUNIPROT:P37287substrate ofInferred only5 paths5 endpoints
- PITPNC1ProteinUNIPROT:Q9UKF7transported byInferred only4 paths4 endpoints
- PITPNM2ProteinUNIPROT:Q9BZ72transported byInferred only1 path1 endpoint
What the reference databases state
Statements
38 statements
38 statements · 1 reference database · Subject: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) · Sources: Rhea
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)CompoundRhea RHEA:19877Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)CompoundRhea RHEA:55652Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)CompoundRhea RHEA:12709Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)CompoundRhea RHEA:12316Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)CompoundRhea RHEA:41147Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate)CompoundRhea RHEA:44680Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of CDIPTProteinRhea RHEA:11580Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of DDHD1ProteinRhea RHEA:35263Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PI4K2AProteinRhea RHEA:19877Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PI4K2BProteinRhea RHEA:19877Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PI4KAProteinRhea RHEA:19877Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PI4KBProteinRhea RHEA:19877Inferred only
Show the remaining 26
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PIGAProteinRhea RHEA:14789Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PIK3C2AProteinRhea RHEA:12709Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PIK3C2BProteinRhea RHEA:12709Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PIK3C2GProteinRhea RHEA:12709Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PIK3C3ProteinRhea RHEA:12709Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PIK3CAProteinRhea RHEA:12709Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PIK3CDProteinRhea RHEA:12709Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PIK3CGProteinRhea RHEA:12709Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PIKFYVEProteinRhea RHEA:44680Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PLCB1ProteinRhea RHEA:43484Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PLCB2ProteinRhea RHEA:43484Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PLCB3ProteinRhea RHEA:43484Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PLCB4ProteinRhea RHEA:43484Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PLCD1ProteinRhea RHEA:43484Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PLCD4ProteinRhea RHEA:43484Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PLCG1ProteinRhea RHEA:43484Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is a substrate of PLCXD2ProteinRhea RHEA:43484Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is transported by CLPTM1LProteinRhea RHEA:38691Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is transported by PITPNAProteinRhea RHEA:38691Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is transported by PITPNBProteinRhea RHEA:38691Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is transported by PITPNC1ProteinRhea RHEA:38691Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is transported by PITPNM1ProteinRhea RHEA:38691Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is transported by PITPNM1ProteinRhea RHEA:86467Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is transported by PITPNM2ProteinRhea RHEA:38691Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is transported by PLTPProteinRhea RHEA:38691Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) is transported by VDAC2ProteinRhea RHEA:38691Inferred only
Reactions
36 reactions
a CDP-1,2-diacyl-sn-glycerol+myo-inositola 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)+CMP+hydron
Catalysed by CDIPT
Reaction pageReversibleBalance undeterminable
Rhea RHEA:11580CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+watera 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)+hydrogenphosphate
Catalysed by SYNJ2 or SYNJ1 or MTM1 or MTMR1 or MTMR2 or MTMR3 or MTMR14 or MTMR8 or SACM1L or MTMR4 or MTMR7 or MTMR6
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:12316CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)+ATP(4-)a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)+ADP(3-)+hydron
Catalysed by PIK3CD or PIK3C2A or PIK3C2B or PIK3C2G or PIK3CA or PIK3CG or PIK3C3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:12709CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)+UDP-N-acetyl-alpha-D-glucosaminea 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol+UDP+hydron
Catalysed by PIGA
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:14789CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)CHEBI:58484+a 1,2-diacyl-sn-glycerol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:17093CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)+watera 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol)+a fatty acid+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:18001CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)+ATP(4-)a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)+ADP(3-)+hydron
Catalysed by PI4KA or PI4K2B or PI4K2A or PI4KB
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:19877CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)+2watersn-glycero-3-phospho-1D-myo-inositol+2a carboxylate+2hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:32983CC BY 4.0Reference data
2a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol)sn-glycero-3-phospho-1D-myo-inositol+a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:33167CC BY 4.0Reference data
a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol)+an acyl-CoAa 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)+coenzyme A(4-)
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:33195CC BY 4.0Reference data
an N-acyl-(4R)-4-hydroxysphinganine+a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)CHEBI:64940+a 1,2-diacyl-sn-glycerol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:33471CC BY 4.0Reference data
an N-acylsphinganine+a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)CHEBI:64941+a 1,2-diacyl-sn-glycerol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:33475CC BY 4.0Reference data
Where it reaches
10 systems, 29 regions, 199 tissues, 368 transporter routes — routes, not measurements: transporters known to carry a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) are expressed there, and no source reports it arriving.
Loading the model…
Other names
5 names
Resolves to: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)
- Also called
- 1-phosphatidyl-1D-myo-inositol anion1-phosphatidyl-1D-myo-inositol anions1,2-diacyl-sn-glycero-3-phospho-1D-myo-inositolPI
- Systematic name
- 2,3-bis(alkanoyloxy)propyl (1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl phosphate