Loading the page.
Proteins/UNIPROT:Q86U10
Exhibits lysophospholipase, transacylase, PAF acetylhydrolase and asparaginase activities (By similarity). Can catalyze three types of transacylation reactions: (1) acyl transfer from 1-acyl-sn-glycero-3-phosphocholine (1-acyl-GPC) to the sn-1(3) positions of glycerol and 2-acylglycerol (sn-1 to -1(3) transfer), (2) acyl transfer from 1-acyl-GPC to the sn-2 positions of 1-acyl-GPC, 1-acyl-sn-glycero-3-phosphoethanolamine (1-acyl-GPE), and other lysophospholipids (sn-1 to -2 transfer) and (3) acyl transfer from 2-acyl-GPC to the sn-1 position of 2-acyl-GPC and 2-acyl-GPE (sn-2 to -1 transfer) (By similarity). Mediates the synthesis of 1-arachidonoyl species of phospholipids by transferring the arachidonoyl residue from 2-arachidonoyl lysophospholipid to the sn-1 position of 2-acyl lysophospholipid (By similarity)..
Function from UniProtKB (Q86U10), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
39 statements
39 statements · 5 reference databases · Subject: ASPG · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea
28 reactions
1-O-acyl-sn-glycero-3-phosphocholine(1+)+waterproton+sn-glycerol 3-phosphocholine+fatty acid
Catalysed by LYPLA2 or PNPLA6 or PLA2G15 or PLA2G4A or LYPLA1 or PNPLA7 or PNPLA8 or PLB1 or ASPG or CLCF1
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.5cytosol
7 names
Resolves to: ASPG
MAM00511c+waterproton+MAM02913c+fatty acid
Catalysed by LYPLA2 or PNPLA6 or PLA2G15 or PLA2G4A or LYPLA1 or PNPLA7 or PNPLA8 or PLB1 or ASPG or CLCF1
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.5cytosol
Human-GEM MAR00645CC BY 4.0Reference data
L-asparagine+waterL-aspartate+proton+ammonium
Reaction pageLeft to rightBalancedEC 3.4.19.5mitochondrial matrix
Human-GEM MAR03862CC BY 4.0Reference data
L-asparagine+waterL-aspartate+proton+ammonium
Reaction pageLeft to rightBalancedEC 3.5.1.1, 3.5.1.38cytosol
Human-GEM MAR04172CC BY 4.0Reference data
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+waterMAM00549c+acetate+proton
Catalysed by PAFAH1B1 or PAFAH1B3 or PAFAH2 or ASPG or PAFAH1B2
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.47cytosol
Human-GEM MAR07611CC BY 4.0Reference data
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+waterMAM00516c+acetate+proton
Catalysed by PAFAH1B1 or PAFAH1B3 or PAFAH2 or ASPG or PAFAH1B2
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.47cytosol
Human-GEM MAR08518CC BY 4.0Reference data
a 1-acyl-sn-glycero-3-phosphocholine+watersn-glycerol 3-phosphocholine+a fatty acid+hydron
Catalysed by PLA2G6 or PLA2G4B or LIPC or PLA2G4A or PLB1 or PNPLA7 or ASPG or PNPLA6 or PLA2G15 or PNPLA8 or PLA2G4C
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:15177CC BY 4.0Reference data
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+watera 1-O-alkyl-sn-glycero-3-phosphocholine+acetate+hydron
Catalysed by LCAT or PAFAH1B2 or PLA2G7 or PAFAH1B3 or ASPG or PAFAH2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:17777CC BY 4.0Reference data
L-asparagine+waterL-aspartate+ammonium
Reaction pageLeft to rightBalanced
Rhea RHEA:21016CC BY 4.0Reference data
a 1-acyl-sn-glycero-3-phosphoethanolamine+watersn-glycero-3-phosphoethanolamine+a fatty acid+hydron
Catalysed by ASPG
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:32967CC BY 4.0Reference data
2a 1-acyl-sn-glycero-3-phosphocholinesn-glycerol 3-phosphocholine+a 1,2-diacyl-sn-glycero-3-phosphocholine
Catalysed by ASPG
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:32991CC BY 4.0Reference data
1-hexadecanoyl-sn-glycero-3-phosphocholine+watersn-glycerol 3-phosphocholine+hexadecanoate+hydron
Catalysed by PLA2G6 or LYPLA1 or LYPLA2 or PLA2G4B or LIPC or CEL or PLA2G4A or PLA2G4E or PLA2G4F or PLB1 or PNPLA7 or GDPD3 and 5 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:40435CC BY 4.0Reference data