Compound
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol
The organophosphate oxoanion formed from 2-monolysocardiolipin by deprotonation of the two phospho groups; principal species present at pH 7.3
Definition from ChEBI (CHEBI:64743), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Structural class, not a single molecule
- Formula
- C12H17O16P2R3
- Mass
- 479.202 g/mol
- Charge
- -2
- SMILES
- [1*]C(=O)OC[C@H](COP(=O)([O-])OCC(O)COP(=O)([O-])OC[C@H](O)COC([3*])=O)OC([2*])=O
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Statements
8 statements
8 statements · 1 reference database · Subject: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol · Sources: Rhea
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol is a substrate of HADHAProteinRhea RHEA:35839Inferred only
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol is a substrate of LCLAT1ProteinRhea RHEA:37611Inferred only
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol is a substrate of LCLAT1ProteinRhea RHEA:37675Inferred only
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol is a substrate of LCLAT1ProteinRhea RHEA:37679Inferred only
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol is a substrate of LCLAT1ProteinRhea RHEA:38623Inferred only
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol is a substrate of LCLAT1ProteinRhea RHEA:38631Inferred only
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol is a substrate of LCLAT1ProteinRhea RHEA:38635Inferred only
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol is a substrate of TAFAZZINProteinRhea RHEA:33731Inferred only
Reactions
14 reactions
a cardiolipin+water1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+a fatty acid+hydron
Catalysed by ABHD18
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:32935CC BY 4.0Reference data
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+a 1,2-diacyl-sn-glycero-3-phosphocholinea cardiolipin+a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by TAFAZZIN
Reaction pageReversibleBalance undeterminable
Rhea RHEA:33731CC BY 4.0Reference data
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+an acyl-CoAa cardiolipin+coenzyme A(4-)
Catalysed by HADHA
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:35839CC BY 4.0Reference data
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+a 1,2-diacyl-sn-glycero-3-phosphoethanolaminea cardiolipin+a 1-acyl-sn-glycero-3-phosphoethanolamine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:35843CC BY 4.0Reference data
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+(9Z)-octadecenoyl-CoA1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho]-glycerol+coenzyme A(4-)
Catalysed by LCLAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:37611CC BY 4.0Reference data
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+(9Z,12Z)-octadecadienoyl-CoA1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerol+coenzyme A(4-)
Catalysed by LCLAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:37675CC BY 4.0Reference data
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+dodecanoyl-CoA1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-dodecanoyl-sn-glycero-3-phospho]-glycerol+coenzyme A(4-)
Catalysed by LCLAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:37679CC BY 4.0Reference data
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+octanoyl-CoA1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerol+coenzyme A(4-)
Catalysed by LCLAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:38623CC BY 4.0Reference data
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+hexadecanoyl-CoA1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-hexadecanoyl-sn-glycero-3-phospho]-glycerol+coenzyme A(4-)
Catalysed by LCLAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:38631CC BY 4.0Reference data
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho]-glycerol+coenzyme A(4-)
Catalysed by LCLAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:38635CC BY 4.0Reference data
1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol+an acyl-CoA1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+coenzyme A(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:39431CC BY 4.0Reference data
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+water1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol+a fatty acid+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:44616CC BY 4.0Reference data
Other names
5 names
Resolves to: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol
- Also called
- 2-MLCL2-monolysocardiolipinMLCLmonolysocardiolipin(2-)monolysocardiolipin(2−)