Compound

a 1,2-diacyl-sn-glycero-3-phosphocholine

A complex mixture of phospholipids; glycolipids; and triglycerides; with substantial amounts of phosphatidylcholines; phosphatidylethanolamines; and phosphatidylinositols, which are sometimes loosely termed as 1,2-diacyl-3-phosphocholines. Lecithin is a component of the cell membrane and commercially extracted from soybeans and EGG yolk. The emulsifying and surfactant properties are useful in food additives and for forming organogels (gels).

Definition from MeSH (D054709), National Library of Medicine, read 2026-09-23. NLM revises MeSH; this copy may not reflect its current record.

CHEBI:57643ChEBI

Open in the graph

Structure

2D depiction

Class: Structural class, not a single molecule
Formula: C10H18NO8PR2
Mass: 311.226 g/mol
Charge: 0
SMILES: [1*]C(=O)OC[C@]([H])(COP(=O)([O-])OCC[N+](C)(C)C)OC([2*])=O
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

40 entities

40 entities reached.

0 reported hops40 assembled from the scaffold

Show the remaining 28

What the reference databases state

Statements

119 statements

119 statements · 1 reference database · Subject: a 1,2-diacyl-sn-glycero-3-phosphocholine · Sources: Rhea

Order

a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine is converted to a 1,2-diacyl-sn-glycero-3-phosphocholineCompoundRhea RHEA:32739Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of ABHD3ProteinRhea RHEA:18689Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of ABHD3ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of DDHD1ProteinRhea RHEA:18689Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of ENPP2ProteinRhea RHEA:14445Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of LCATProteinRhea RHEA:21204Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of LIPCProteinRhea RHEA:18689Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of LIPGProteinRhea RHEA:18689Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of LPGAT1ProteinRhea RHEA:10332Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of LPLProteinRhea RHEA:18689Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of LRATProteinRhea RHEA:17469Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PGAP6ProteinRhea RHEA:15801Inferred only

Show the remaining 107

a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G10ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G12AProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:78043Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:44508Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:78443Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:78439Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:78435Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:78431Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:78143Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:78139Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:78135Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:78131Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:78059Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:78055Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:18689Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:44512Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:78039Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G1BProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G2AProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G2DProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G2EProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G2FProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G3ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4AProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4BProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4CProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4DProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4EProteinRhea RHEA:45188Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4EProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4FProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G5ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLA2G6ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT1ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT1ProteinRhea RHEA:18689Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT2ProteinRhea RHEA:18689Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT2ProteinRhea RHEA:45192Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT2ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT2ProteinRhea RHEA:45188Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT3ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT3ProteinRhea RHEA:18689Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT4ProteinRhea RHEA:18689Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT4ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT5ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT5ProteinRhea RHEA:45188Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT5ProteinRhea RHEA:45192Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLAAT5ProteinRhea RHEA:18689Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLB1ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLD1ProteinRhea RHEA:44868Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLD1ProteinRhea RHEA:14445Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PLD2ProteinRhea RHEA:14445Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PNLIPRP2ProteinRhea RHEA:44664Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PNPLA2ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PNPLA3ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PNPLA4ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PNPLA8ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PNPLA8ProteinRhea RHEA:18689Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PRDX6ProteinRhea RHEA:15801Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of PTDSS1ProteinRhea RHEA:45088Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of SGMS1ProteinRhea RHEA:44620Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of SGMS1ProteinRhea RHEA:41796Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of SGMS1ProteinRhea RHEA:42152Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of SGMS1ProteinRhea RHEA:18765Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of SGMS1ProteinRhea RHEA:42140Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of SGMS2ProteinRhea RHEA:42140Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of SGMS2ProteinRhea RHEA:42152Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of SGMS2ProteinRhea RHEA:41796Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of SGMS2ProteinRhea RHEA:44620Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of SGMS2ProteinRhea RHEA:18765Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of SMPD1ProteinRhea RHEA:10604Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of TAFAZZINProteinRhea RHEA:33731Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is a substrate of TMEM68ProteinRhea RHEA:77743Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ABCA1ProteinRhea RHEA:38583Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ABCA3ProteinRhea RHEA:66272Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ABCA7ProteinRhea RHEA:38583Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ABCB1ProteinRhea RHEA:38583Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ABCB4ProteinRhea RHEA:66272Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ANO3ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ANO4ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ANO6ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ANO7ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ANO9ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ATG9AProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ATG9BProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ATP10AProteinRhea RHEA:38583Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ATP8B1ProteinRhea RHEA:38583Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by ATP8B2ProteinRhea RHEA:38583Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by CLPTM1LProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by MTTPProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by OSBPL3ProteinRhea RHEA:85491Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by PCTPProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by PITPNAProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by PITPNBProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by PLSCR1ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by PLSCR2ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by PLSCR3ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by PLSCR4ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by PLTPProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by SERINC2ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by SERINC3ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by SERINC5ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by STARD7ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by TMEM41BProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by TMEM63BProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by VDAC1ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by VDAC2ProteinRhea RHEA:38571Inferred only
a 1,2-diacyl-sn-glycero-3-phosphocholine is transported by VMP1ProteinRhea RHEA:38571Inferred only

Reactions

83 reactions

a 2-acyl-sn-glycero-3-phosphocholine+an acyl-CoAa 1,2-diacyl-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by LPGAT1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:10332CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phosphocholine+waterphosphocholine+a 1,2-diacyl-sn-glycerol+hydron
Catalysed by SMPD1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:10604CC BY 4.0Reference data
a 1-acyl-sn-glycero-3-phosphocholine+an acyl-CoAa 1,2-diacyl-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by PRDX6 or LPCAT4 or LPCAT3 or MBOAT1 or MBOAT2 or LPCAT2 or LPCAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:12937CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phosphocholine+watera 1,2-diacyl-sn-glycero-3-phosphate+choline+hydron
Catalysed by PLD2 or PLD1 or ENPP2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:14445CC BY 4.0Reference data
a CDP-1,2-diacyl-sn-glycerol+cholinea 1,2-diacyl-sn-glycero-3-phosphocholine+CMP+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:14597CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phosphocholine+watera 1-acyl-sn-glycero-3-phosphocholine+a fatty acid+hydron
Catalysed by PLA2G10 or PLA2G6 or PLA2G1B or PLA2G4B or PLA2G2A or PRDX6 or PLA2G5 or PNPLA4 or PLA2G4A or PLAAT3 or PLA2G4E or PLA2G4F and 18 more alternatives
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:15801CC BY 4.0Reference data
all-trans-retinol--[retinol-binding protein]+a 1,2-diacyl-sn-glycero-3-phosphocholineapo--[retinol-binding protein]+an all-trans-retinyl ester+a 2-acyl-sn-glycero-3-phosphocholine
Catalysed by LRAT
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:17469CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phosphocholine+watera 2-acyl-sn-glycero-3-phosphocholine+a fatty acid+hydron
Catalysed by LPL or LIPC or PLAAT3 or PLA2G15 or DDHD1 or ABHD3 or PLAAT5 or PLAAT1 or PNPLA8 or PLAAT2 or PLAAT4 or LIPG
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:18689CC BY 4.0Reference data
an N-acylsphing-4-enine+a 1,2-diacyl-sn-glycero-3-phosphocholinea sphingomyelin+a 1,2-diacyl-sn-glycerol
Catalysed by SGMS1 or SGMS2
Reaction pageReversibleBalance undeterminable
Rhea RHEA:18765CC BY 4.0Reference data
a di-trans,poly-cis-dolichol+a 1,2-diacyl-sn-glycero-3-phosphocholinean acyl-di-trans,poly-cis-dolichol+a 1-acyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:19285CC BY 4.0Reference data
a sterol+a 1,2-diacyl-sn-glycero-3-phosphocholinea sterol ester+a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by LCAT
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:21204CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine+S-adenosyl-L-methioninea 1,2-diacyl-sn-glycero-3-phosphocholine+S-adenosyl-L-homocysteine+hydron
Catalysed by PEMT
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:32739CC BY 4.0Reference data

Show the remaining 71

Where it reaches

10 systems, 29 regions, 263 tissues, 1,509 transporter routes — routes, not measurements: transporters known to carry a 1,2-diacyl-sn-glycero-3-phosphocholine are expressed there, and no source reports it arriving.

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Nervous

Endocrine

Respiratory

Cardiovascular

Digestive

Urinary

Reproductive

Blood and immune

Musculoskeletal

Skin and adipose

Other names

10 names

Resolves to: a 1,2-diacyl-sn-glycero-3-phosphocholine

Also called: 1,2-diacyl-sn-glycero-3-phosphocholine1,2-diacyl-sn-glycero-3-phosphocholine betaine1,2-diacyl-sn-glycero-3-phosphocholines3-sn-phosphatidylcholine3-sn-phosphatidylcholinesDiacyl PCDiacylphosphatidylcholinelecithinPCPhosphatidylcholine