Compound
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)
A phosphatidylglycerol(1−) in which the phosphatidyl moiety has R-configuration and the glycerol moiety has S-configuration.
Definition from ChEBI (CHEBI:64716), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Structural class, not a single molecule
- Formula
- C8H12O10PR2
- Mass
- 299.149 g/mol
- Charge
- -1
- SMILES
- *C(=O)OC[C@H](COP(=O)([O-])OC[C@@H](O)CO)OC(*)=O
- Look it up
- ChEBI
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
8 entities
8 entities reached.
0 reported hops8 assembled from the scaffold
- VAT1ProteinUNIPROT:Q99536transported byInferred only92 paths92 endpoints
- PLTPProteinUNIPROT:P55058transported byInferred only44 paths44 endpoints
- PLSCR3ProteinUNIPROT:Q9NRY6transported byInferred only42 paths42 endpoints
- ABCA3ProteinUNIPROT:Q99758transported byInferred only36 paths36 endpoints
- PLA2G15ProteinUNIPROT:Q8NCC3substrate ofInferred only20 paths5 endpoints
- TAFAZZINProteinUNIPROT:Q16635substrate ofInferred only8 paths8 endpoints
- CRLS1ProteinUNIPROT:Q9UJA2substrate ofInferred only8 paths8 endpoints
- DDHD1ProteinUNIPROT:Q8NEL9substrate ofInferred only5 paths5 endpoints
What the reference databases state
Statements
14 statements
14 statements · 1 reference database · Subject: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) · Sources: Rhea
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)CompoundRhea RHEA:33751Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)CompoundRhea RHEA:34079Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) is converted to a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate)CompoundRhea RHEA:34079Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of CRLS1ProteinRhea RHEA:32931Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of DDHD1ProteinRhea RHEA:67428Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of PLA2G15ProteinRhea RHEA:67428Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of PLA2G15ProteinRhea RHEA:44416Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of PLA2G15ProteinRhea RHEA:78359Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of PLA2G15ProteinRhea RHEA:78363Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) is a substrate of TAFAZZINProteinRhea RHEA:67748Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) is transported by ABCA3ProteinRhea RHEA:66344Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) is transported by PLSCR3ProteinRhea RHEA:39743Inferred only
Show the remaining 2
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) is transported by PLTPProteinRhea RHEA:39743Inferred only
- a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) is transported by VAT1ProteinRhea RHEA:39743Inferred only
Reactions
20 reactions
L-lysyl-tRNA(Lys)+a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)CHEBI:75792+tRNA(Lys)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:10668CC BY 4.0Reference data
L-alanyl-tRNA(Ala)+a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)CHEBI:75793+tRNA(Ala)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:20489CC BY 4.0Reference data
2a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)a cardiolipin+glycerol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:31451CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)+watersn-glycerol 3-phosphate+a 1,2-diacyl-sn-glycerol+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:32927CC BY 4.0Reference data
a CDP-1,2-diacyl-sn-glycerol+a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)a cardiolipin+CMP+hydron
Catalysed by CRLS1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:32931CC BY 4.0Reference data
1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)+an acyl-CoAa 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)+coenzyme A(4-)
Catalysed by LCLAT1 or LPCAT1 or GPAM
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:33203CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate)+watera 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)+hydrogenphosphate
Catalysed by PTPMT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:33751CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate)+ADP(3-)+hydrona 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)+ATP(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:34079CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)
Transported by PLTP or VAT1 or PLSCR3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:39743CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)+a 1,2-diacyl-sn-glycero-3-phosphoethanolaminea cardiolipin+ethanolamine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:42972CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)+water1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)+a fatty acid+hydron
Catalysed by PLA2G15
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:44416CC BY 4.0Reference data
a cardiolipin+watera 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)+a 1,2-diacyl-sn-glycero-3-phosphate+hydron
Catalysed by PLD6
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:44884CC BY 4.0Reference data
Where it reaches
10 systems, 29 regions, 128 tissues, 210 transporter routes — routes, not measurements: transporters known to carry a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) are expressed there, and no source reports it arriving.
Loading the model…
Other names
2 names
Resolves to: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)
- Also called
- 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)PG