Compound
ethanolamine
A viscous, hygroscopic amino alcohol with an ammoniacal odor. It is widely distributed in biological tissue and is a component of lecithin. It is used as a surfactant, fluorimetric reagent, and to remove CO2 and H2S from natural gas and other gases.
Structure
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- Class
- Organic compound, cation
- Formula
- C2H8NO
- Mass
- 62.092 g/mol
- Charge
- +1
- InChIKey
- HZAXFHJVJLSVMW-UHFFFAOYSA-O
- SMILES
- [NH3+]CCO
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
10 entities
10 entities reached.
0 reported hops10 assembled from the scaffold
- SLC44A2ProteinUNIPROT:Q8IWA5transported byInferred only74 paths74 endpoints
- SLC44A1ProteinUNIPROT:Q8WWI5transported byInferred only64 paths62 endpoints
- CHKAProteinUNIPROT:P35790substrate ofInferred only32 paths16 endpoints
- CHKBProteinUNIPROT:Q9Y259substrate ofInferred only22 paths11 endpoints
- ETNK2ProteinUNIPROT:Q9NVF9substrate ofInferred only18 paths9 endpoints
- ETNK1ProteinUNIPROT:Q9HBU6substrate ofInferred only16 paths8 endpoints
- FLVCR2ProteinUNIPROT:Q9UPI3transported byInferred only13 paths13 endpoints
- FAAHProteinUNIPROT:O00519substrate ofInferred only6 paths6 endpoints
- ENPP2ProteinUNIPROT:Q13822substrate ofInferred only5 paths5 endpoints
- FLVCR1ProteinUNIPROT:Q9Y5Y0transported byInferred only3 paths3 endpoints
What the reference databases state
Statements
23 statements
23 statements · 2 reference databases · Subject: ethanolamine · Sources: Human-GEM, Rhea
- ethanolamine is converted to acetaldehydeCompoundHuman-GEM MAR00647Inferred only
- ethanolamine is converted to acetaldehydeCompoundRhea RHEA:15313Inferred only
- acetaldehyde is converted to ethanolamineCompoundRhea RHEA:15313Inferred only
- glycolaldehyde is converted to ethanolamineCompoundRhea RHEA:18581Inferred only
- ethanolamine is converted to glycolaldehydeCompoundRhea RHEA:18581Inferred only
- O-phosphoethanolamine is converted to ethanolamineCompoundHuman-GEM MAR00649Inferred only
- ethanolamine is converted to O-phosphoethanolamineCompoundHuman-GEM MAR00648Inferred only
- ethanolamine is converted to phosphoethanolamineCompoundRhea RHEA:13069Inferred only
- phosphoethanolamine is converted to ethanolamineCompoundRhea RHEA:16089Inferred only
- ethanolamine is a substrate of CHKAProteinRhea RHEA:13069Inferred only
- ethanolamine is a substrate of CHKAProteinHuman-GEM MAR00648Inferred only
- ethanolamine is a substrate of CHKBProteinRhea RHEA:13069Inferred only
Show the remaining 11
- ethanolamine is a substrate of CHKBProteinHuman-GEM MAR00648Inferred only
- ethanolamine is a substrate of ENPP2ProteinRhea RHEA:15965Inferred only
- ethanolamine is a substrate of ETNK1ProteinRhea RHEA:13069Inferred only
- ethanolamine is a substrate of ETNK1ProteinHuman-GEM MAR00648Inferred only
- ethanolamine is a substrate of ETNK2ProteinRhea RHEA:13069Inferred only
- ethanolamine is a substrate of ETNK2ProteinHuman-GEM MAR00648Inferred only
- ethanolamine is a substrate of FAAHProteinHuman-GEM MAR01346Inferred only
- ethanolamine is transported by FLVCR1ProteinRhea RHEA:32747Inferred only
- ethanolamine is transported by FLVCR2ProteinRhea RHEA:32747Inferred only
- ethanolamine is transported by SLC44A1ProteinRhea RHEA:75467Inferred only
- ethanolamine is transported by SLC44A2ProteinRhea RHEA:75467Inferred only
Reactions
58 reactions
phosphatidylethanolamine+L-seryl residueethanolamine+phosphatidyl-L-serine
Catalysed by PTDSS2
Reaction pageLeft to rightBalance undeterminableEC 2.7.8.29cytosol
Human-GEM MAR00622CC BY 4.0Reference data
water+phosphatidylethanolamineethanolamine+proton+phosphatidic acid
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4cytosol
Human-GEM MAR00642CC BY 4.0Reference data
water+MAM02913cethanolamine+proton+CHEBI:15978
Catalysed by GPCPD1
Reaction pageLeft to rightBalancedEC 3.1.4.2cytosol
Human-GEM MAR00646CC BY 4.0Reference data
ethanolamineacetaldehyde+proton+ammonium
Reaction pageLeft to rightBalancedEC 4.3.1.7cytosol
Human-GEM MAR00647CC BY 4.0Reference data
ATP+ethanolamineADP+O-phosphoethanolamine+proton
Catalysed by CHKB or CHKA or ETNK1 or ETNK2
Reaction pageLeft to rightBalancedEC 2.7.1.82cytosol
Human-GEM MAR00648CC BY 4.0Reference data
O-phosphoethanolamine+waterethanolamine+phosphate(3-)
Catalysed by PHOSPHO1
Reaction pageLeft to rightBalancedEC 3.1.3.75cytosol
Human-GEM MAR00649CC BY 4.0Reference data
(5Z,8Z,11Z,14Z)-eicosatetraenoate+ethanolamineN-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine+water
Catalysed by FAAH
Reaction pageLeft to rightBalancedEC 3.5.1.99cytosol
Human-GEM MAR01346CC BY 4.0Reference data
water+1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamineMAM00627c+ethanolamine+proton
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4cytosol
Human-GEM MAR07605CC BY 4.0Reference data
1-(alk-1-enyl)-sn-glycero-3-phosphoethanolamine+proton+waterMAM00222c+ethanolamine
Catalysed by ENPP2
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.39cytosol
Human-GEM MAR07607CC BY 4.0Reference data
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR07896CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09084CC BY 4.0Reference data
water+N-hexadecanoylethanolamineethanolamine+hexadecanoic acid
Catalysed by NAAA
Reaction pageLeft to rightBalancedEC 3.5.1.60, 3.5.1.99cytosol
Human-GEM MAR20093CC BY 4.0Reference data
Where it reaches
10 systems, 25 regions, 131 tissues, 152 transporter routes — routes, not measurements: transporters known to carry ethanolamine are expressed there, and no source reports it arriving.
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Other names
3 names
Resolves to: ethanolamine
- Also called
- 2-hydroxyethan-1-aminiumethanolaminium cation
- Systematic name
- 2-hydroxyethanaminium