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Proteins/UNIPROT:Q6ZV29
Lysophospholipase which preferentially deacylates unsaturated lysophosphatidylcholine (C18:1), generating glycerophosphocholine. Also can deacylate, to a lesser extent, lysophosphatidylethanolamine (C18:1), lysophosphatidyl-L-serine (C18:1) and lysophosphatidic acid (C16:0)..
Function from UniProtKB (Q6ZV29), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
30 statements
30 statements · 4 reference databases · Subject: PNPLA7 · Sources: Hetionet, Human-GEM, Reactome, Rhea
8 reactions
1-O-acyl-sn-glycero-3-phosphocholine(1+)+waterproton+sn-glycerol 3-phosphocholine+fatty acid
Catalysed by LYPLA2 or PNPLA6 or PLA2G15 or PLA2G4A or LYPLA1 or PNPLA7 or PNPLA8 or PLB1 or ASPG or CLCF1
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.5cytosol
1 name
Resolves to: PNPLA7
MAM00511c+waterproton+MAM02913c+fatty acid
Catalysed by LYPLA2 or PNPLA6 or PLA2G15 or PLA2G4A or LYPLA1 or PNPLA7 or PNPLA8 or PLB1 or ASPG or CLCF1
Reaction pageLeft to rightBalance undeterminableEC 3.1.1.5cytosol
Human-GEM MAR00645CC BY 4.0Reference data
a 1-acyl-sn-glycero-3-phosphocholine+watersn-glycerol 3-phosphocholine+a fatty acid+hydron
Catalysed by PLA2G6 or PLA2G4B or LIPC or PLA2G4A or PLB1 or PNPLA7 or ASPG or PNPLA6 or PLA2G15 or PNPLA8 or PLA2G4C
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:15177CC BY 4.0Reference data
1-hexadecanoyl-sn-glycero-3-phosphocholine+watersn-glycerol 3-phosphocholine+hexadecanoate+hydron
Catalysed by PLA2G6 or LYPLA1 or LYPLA2 or PLA2G4B or LIPC or CEL or PLA2G4A or PLA2G4E or PLA2G4F or PLB1 or PNPLA7 or GDPD3 and 5 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:40435CC BY 4.0Reference data
1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine+watersn-glycero-3-phospho-L-serine+(9Z)-octadecenoate+hydron
Catalysed by LIPC or PLA1A or PNPLA7 or ABHD12
Reaction pageLeft to rightBalanced
Rhea RHEA:40499CC BY 4.0Reference data
1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine+watersn-glycerol 3-phosphocholine+(9Z)-octadecenoate+hydron
Catalysed by PNPLA7 or ASPG or PNPLA6
Reaction pageLeft to rightBalanced
Rhea RHEA:40807CC BY 4.0Reference data
1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine+watersn-glycero-3-phosphoethanolamine+(9Z)-octadecenoate+hydron
Catalysed by PNPLA7 or ASPG or ABHD12
Reaction pageLeft to rightBalanced
Rhea RHEA:40895CC BY 4.0Reference data
1-hexadecanoyl-sn-glycero-3-phosphate+watersn-glycerol 3-phosphate+hexadecanoate+hydron
Catalysed by LYPLA2 or PNPLA7 or PNPLA6
Reaction pageLeft to rightBalanced
Rhea RHEA:49092CC BY 4.0Reference data