Compound

a 1,2-diacyl-sn-glycero-3-phosphoethanolamine

An optically active phosphatidylethanolamine zwitterion having R-configuration

Definition from ChEBI (CHEBI:64612), read 2026-09-23. CC BY 4.0.

CHEBI:64612ChEBI

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Structure

2D depiction

Class: Structural class, not a single molecule
Formula: C7H12NO8PR2
Mass: 269.146 g/mol
Charge: 0
SMILES: [1*]C(=O)OC[C@H](COP(=O)([O-])OCC[NH3+])OC([2*])=O
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

37 entities

37 entities reached.

0 reported hops37 assembled from the scaffold

Show the remaining 25

What the reference databases state

Statements

55 statements

55 statements · 1 reference database · Subject: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine · Sources: Rhea

Order

a 1,2-diacyl-sn-glycero-3-phospho-L-serine is converted to a 1,2-diacyl-sn-glycero-3-phosphoethanolamineCompoundRhea RHEA:20828Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is converted to a 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamineCompoundRhea RHEA:11164Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of DDHD1ProteinRhea RHEA:44408Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PEMTProteinRhea RHEA:11164Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PIGGProteinRhea RHEA:61016Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PIGNProteinRhea RHEA:83767Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PIGNProteinRhea RHEA:60896Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PIGOProteinRhea RHEA:61012Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G15ProteinRhea RHEA:44532Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G15ProteinRhea RHEA:44536Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G15ProteinRhea RHEA:44604Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G2AProteinRhea RHEA:44604Inferred only

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a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G2DProteinRhea RHEA:44604Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G2EProteinRhea RHEA:44604Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PLA2G4EProteinRhea RHEA:45188Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT2ProteinRhea RHEA:45192Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT2ProteinRhea RHEA:45188Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT5ProteinRhea RHEA:45192Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PLAAT5ProteinRhea RHEA:45188Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PNPLA8ProteinRhea RHEA:44604Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PTDSS1ProteinRhea RHEA:27606Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of PTDSS2ProteinRhea RHEA:27606Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of SAMD8ProteinRhea RHEA:42144Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of SAMD8ProteinRhea RHEA:42148Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of SAMD8ProteinRhea RHEA:42136Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of SAMD8ProteinRhea RHEA:42128Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of SAMD8ProteinRhea RHEA:36079Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of SAMD8ProteinRhea RHEA:78951Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of SGMS1ProteinRhea RHEA:36079Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of SGMS2ProteinRhea RHEA:36079Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of SGMS2ProteinRhea RHEA:42128Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of SGMS2ProteinRhea RHEA:42148Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of SGMS2ProteinRhea RHEA:42144Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is a substrate of SGMS2ProteinRhea RHEA:42136Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by ABCA4ProteinRhea RHEA:66132Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by ABCB1ProteinRhea RHEA:36439Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by ABCB4ProteinRhea RHEA:36439Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by ATG2AProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by ATG2BProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by ATG9AProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by ATG9BProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by ATP11AProteinRhea RHEA:66132Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by ATP11BProteinRhea RHEA:66132Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by ATP11CProteinRhea RHEA:66132Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by ATP8A2ProteinRhea RHEA:36439Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by CLPTM1LProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by MTTPProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by PLSCR1ProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by PLSCR3ProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by PLTPProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by SERINC2ProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by SERINC3ProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by SERINC5ProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by TMEM41BProteinRhea RHEA:38895Inferred only
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine is transported by VMP1ProteinRhea RHEA:38895Inferred only

Reactions

49 reactions

a 2-acyl-sn-glycero-3-phosphoethanolamine+a fatty acyl-[ACP]a 1,2-diacyl-sn-glycero-3-phosphoethanolamine+holo-[ACP]
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:10304CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine+S-adenosyl-L-methioninea 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine+S-adenosyl-L-homocysteine+hydron
Catalysed by PEMT
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:11164CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phospho-L-serine+hydrona 1,2-diacyl-sn-glycero-3-phosphoethanolamine+carbon dioxide
Catalysed by PISD
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:20828CC BY 4.0Reference data
CHEBI:58540+a 1,2-diacyl-sn-glycero-3-phosphoethanolamineCHEBI:60085+a 1,2-diacyl-sn-glycerol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:24698CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine+L-seryl residuea 1,2-diacyl-sn-glycero-3-phospho-L-serine+ethanolamine
Catalysed by PTDSS1 or PTDSS2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:27606CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine+a 1,2-diacyl-sn-glycerola triacyl-sn-glycerol+a 1-acyl-sn-glycero-3-phosphoethanolamine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:32847CC BY 4.0Reference data
a 2-acylglycerol+a 1,2-diacyl-sn-glycero-3-phosphoethanolaminea 1-acyl-sn-glycero-3-phosphoethanolamine+a 1,2-diacyl-sn-glycerol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:32855CC BY 4.0Reference data
a 1-acyl-sn-glycerol+a 1,2-diacyl-sn-glycero-3-phosphoethanolaminea 1-acyl-sn-glycero-3-phosphoethanolamine+a 1,2-diacyl-sn-glycerol
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:32863CC BY 4.0Reference data
CDP-ethanolamine+a 1,2-diacyl-sn-glycerola 1,2-diacyl-sn-glycero-3-phosphoethanolamine+CMP+hydron
Catalysed by SELENOI or CEPT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:32943CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine+2watersn-glycero-3-phosphoethanolamine+2a carboxylate+2hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:32971CC BY 4.0Reference data
a 1-acyl-sn-glycero-3-phosphoethanolamine+an acyl-CoAa 1,2-diacyl-sn-glycero-3-phosphoethanolamine+coenzyme A(4-)
Catalysed by LPCAT4 or LPCAT3 or MBOAT1 or MBOAT2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:32995CC BY 4.0Reference data
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol+a 1,2-diacyl-sn-glycero-3-phosphoethanolaminea cardiolipin+a 1-acyl-sn-glycero-3-phosphoethanolamine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:35843CC BY 4.0Reference data

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Where it reaches

10 systems, 29 regions, 238 tissues, 734 transporter routes — routes, not measurements: transporters known to carry a 1,2-diacyl-sn-glycero-3-phosphoethanolamine are expressed there, and no source reports it arriving.

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Nervous

Endocrine

Respiratory

Cardiovascular

Digestive

Urinary

Reproductive

Blood and immune

Musculoskeletal

Skin and adipose

Other names

3 names

Resolves to: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine

Also called: (2R)-1,2-diacylglycero-3-phosphoethanolamine zwitterion1,2-diacyl-sn-glycero-3-phosphoethanolaminePE