Compound

a 1-O-alkyl-sn-glycero-3-phosphocholine

A glycerophosphocholine that consists of L-α-glycerophosphocholine carrying an unspecified alkyl substituent at position 1.

Definition from ChEBI (CHEBI:30909), read 2026-09-23. CC BY 4.0.

CHEBI:30909ChEBI

Open in the graph

Structure

2D depiction

Class: Organic compound
Formula: C8H19NO6PR
Mass: 256.214 g/mol
Charge: 0
SMILES: *OC[C@@H](O)COP(=O)([O-])OCC[N+](C)(C)C
Look it up: ChEBI

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

6 entities

6 entities reached.

0 reported hops6 assembled from the scaffold

What the reference databases state

Statements

8 statements

8 statements · 1 reference database · Subject: a 1-O-alkyl-sn-glycero-3-phosphocholine · Sources: Rhea

Order

a 1-O-alkyl-sn-glycero-3-phosphocholine is converted to a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholineCompoundRhea RHEA:18461Inferred only
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine is converted to a 1-O-alkyl-sn-glycero-3-phosphocholineCompoundRhea RHEA:18461Inferred only
a 1-O-alkyl-sn-glycero-3-phosphocholine is a substrate of ENPP2ProteinRhea RHEA:39927Inferred only
a 1-O-alkyl-sn-glycero-3-phosphocholine is a substrate of ENPP6ProteinRhea RHEA:36083Inferred only
a 1-O-alkyl-sn-glycero-3-phosphocholine is a substrate of GDPD1ProteinRhea RHEA:39927Inferred only
a 1-O-alkyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:18461Inferred only
a 1-O-alkyl-sn-glycero-3-phosphocholine is a substrate of LPCAT2ProteinRhea RHEA:18461Inferred only
a 1-O-alkyl-sn-glycero-3-phosphocholine is a substrate of LPCAT4ProteinRhea RHEA:18461Inferred only

Reactions

14 reactions

a 1-organyl-2-lyso-sn-glycero-3-phospholipid+a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholinea 1-organyl-2-acetyl-sn-glycero-3-phospholipid+a 1-O-alkyl-sn-glycero-3-phosphocholine
Catalysed by PAFAH2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:11048CC BY 4.0Reference data
CHEBI:28894+a 1-O-alkyl-sn-glycero-3-phosphoethanolamineCHEBI:76251+a 1-O-alkyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:15409CC BY 4.0Reference data
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+watera 1-O-alkyl-sn-glycero-3-phosphocholine+acetate+hydron
Catalysed by LCAT or PAFAH1B2 or PLA2G7 or PAFAH1B3 or ASPG or PAFAH2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:17777CC BY 4.0Reference data
a 1-O-alkyl-sn-glycero-3-phosphocholine+acetyl-CoAa 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by LPCAT4 or LPCAT2 or LPCAT1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:18461CC BY 4.0Reference data
a 1-O-alkyl-sn-glycero-3-phosphoethanolamine+a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholinea 1-O-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine+a 1-O-alkyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:20972CC BY 4.0Reference data
a 1-O-alkyl-sn-glycero-3-phosphocholine+an acyl-CoAa 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+coenzyme A(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:23992CC BY 4.0Reference data
a 1-O-alkyl-sn-glycero-3-phosphocholine+watera 1-O-alkyl-sn-glycerol+phosphocholine+hydron
Catalysed by ENPP6
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:36083CC BY 4.0Reference data
a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+watera 1-O-alkyl-sn-glycero-3-phosphocholine+a fatty acid+hydron
Catalysed by PLA2G6 or PLA2G4A or PLA2G4F or PLB1 or PAFAH2 or PLA2G4C
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:36231CC BY 4.0Reference data
a 1-O-alkyl-sn-glycero-3-phosphocholine+(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoACHEBI:28894+coenzyme A(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:37715CC BY 4.0Reference data
a 1-O-alkyl-sn-glycero-3-phosphocholine+watera 1-O-alkyl-sn-glycero-3-phosphate+choline+hydron
Catalysed by ENPP2 or GDPD1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:39927CC BY 4.0Reference data
a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+sphing-4-eninea 1-O-alkyl-sn-glycero-3-phosphocholine+an N-acylsphing-4-enine+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:44660CC BY 4.0Reference data
a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine+a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolaminea 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine+a 1-O-alkyl-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:44684CC BY 4.0Reference data

Show the remaining 2

Other names

7 names

Resolves to: a 1-O-alkyl-sn-glycero-3-phosphocholine

Also called: 1-Alkyl-2-lyso-sn-glycero-3-phosphocholine1-alkyl-sn-glycero-3-phosphocholine1-O-alkyl-sn-glycero-3-phosphocholine1-Organyl-2-lyso-sn-glycero-3-phosphocholine1-Radyl-2-lyso-sn-glycero-3-phosphocholineLPC-OLPC(O-)