Compound
alpha-NAD(+)
An organophosphate oxoanion obtained by deprotonation of the two diphosphate OH groups of α-NAD(1+); major species at pH 7.3.
Definition from ChEBI (CHEBI:77017), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C21H26N7O14P2
- Mass
- 662.422 g/mol
- Charge
- -1
- InChIKey
- BAWFJGJZGIEFAR-OPDHFMQKSA-M
- SMILES
- NC(=O)c1ccc[n+]([C@H]2O[C@H](COP(=O)([O-])OP(=O)([O-])OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)c1
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
What the reference databases state
Statements
8 statements
8 statements · 2 reference databases · Subject: alpha-NAD(+) · Sources: Human-GEM, Rhea
- alpha-NAD(+) is a substrate of ADPRHProteinRhea RHEA:68792Inferred only
- alpha-NAD(+) is a substrate of ADPRSProteinRhea RHEA:68792Inferred only
- alpha-NAD(+) is a substrate of MACROD1ProteinRhea RHEA:68792Inferred only
- alpha-NAD(+) is a substrate of MACROD1ProteinHuman-GEM MAR20100Inferred only
- alpha-NAD(+) is a substrate of MACROD2ProteinHuman-GEM MAR20100Inferred only
- alpha-NAD(+) is a substrate of MACROD2ProteinRhea RHEA:68792Inferred only
- alpha-NAD(+) is a substrate of OARD1ProteinHuman-GEM MAR20100Inferred only
- alpha-NAD(+) is a substrate of OARD1ProteinRhea RHEA:68792Inferred only
Reactions
2 reactions
water+alpha-NAD(+)ADP-D-ribose+proton+nicotinamide
Catalysed by MACROD2 or MACROD1 or OARD1
Reaction pageLeft to rightBalancedEC 3.1.1.106nucleus
Human-GEM MAR20100CC BY 4.0Reference data
alpha-NAD(+)+waterADP-D-ribose+nicotinamide+hydron
Catalysed by MACROD2 or ADPRH or MACROD1 or ADPRS or OARD1
Reaction pageDirection not assertedBalanced
Rhea RHEA:68792CC BY 4.0Reference data