fumaric acid
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
303 compounds within 3 steps: 11 in 1, 56 in 2, 236 in 3
Two steps
- transport of fumarate and sulfate (cytosol to mitochondria)
- (3S)-citramalate(in) + sulfate(out) = (3S)-citramalate(out) + sulfate(in)
Catalysed by SLC25A10, SLC25A14, SLC25A30mitochondrial matrix, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes
Catalysed by FH, SLC25A1cytosol, mitochondrial matrixOne of 3 routes
- transport of fumarate and sulfite (cytosol to mitochondria)
- thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
Catalysed by SLC25A10, TSTD1mitochondrial matrix, cytosolOne of 2 routes
Catalysed by SLC25A10, PAPSS1, PAPSS2mitochondrial matrix, cytosolOne of 4 routes
- 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase
- 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase
Catalysed by ADSLcytosolOne of 2 routes
- transport of fumarate and thiosulfate (cytosol to mitochondria)
- thiosulfate + glutathione = S-sulfanylglutathione + sulfite + H(+)
Catalysed by SLC25A10, TSTD1mitochondrial matrix, cytosolOne of 3 routes
Catalysed by SLC25A10, SLC4A1mitochondrial matrix, cytosol, extracellular spaceOne of 2 routes