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Proteins/UNIPROT:Q9UPQ9
Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffolding protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes..
Function from UniProtKB (Q9UPQ9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
99 statements
99 statements · 4 reference databases · Subject: TNRC6B · Sources: gene ontology, Hetionet, Human-GEM, Reactome
1 reaction
AMP+fumaric acidN(6)-(1,2-dicarboxyethyl)-AMP
Reaction pageReversibleBalancedEC 4.3.2.2cytosol
Human-GEM MAR04412CC BY 4.0Reference data
2 names
Resolves to: TNRC6B