Compound
IMP
Inosine 5'-Monophosphate. A purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.
Structure
No depiction stored
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- Class
- Organic compound, anion
- Formula
- C10H11N4O8P
- Mass
- 346.192 g/mol
- Charge
- -2
- InChIKey
- GRSZFWQUAKGDAV-KQYNXXCUSA-L
- SMILES
- O=c1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)([O-])[O-])[C@@H](O)[C@H]1O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
11 entities
11 entities reached.
0 reported hops11 assembled from the scaffold
- NT5C2ProteinUNIPROT:P49902substrate ofInferred only84 paths12 endpoints
- SLC25A36ProteinUNIPROT:Q96CQ1transported byInferred only39 paths39 endpoints
- IMPDH2ProteinUNIPROT:P12268substrate ofInferred only30 paths30 endpoints
- IMPDH1ProteinUNIPROT:P20839substrate ofInferred only22 paths22 endpoints
- NT5EProteinUNIPROT:P21589substrate ofInferred only21 paths21 endpoints
- ADSS2ProteinUNIPROT:P30520substrate ofInferred only10 paths10 endpoints
- NT5CProteinUNIPROT:Q8TCD5substrate ofInferred only8 paths8 endpoints
- GMPRProteinUNIPROT:P36959substrate ofInferred only8 paths8 endpoints
- NT5C1AProteinUNIPROT:Q9BXI3substrate ofInferred only5 paths5 endpoints
- ADSS1ProteinUNIPROT:Q8N142substrate ofInferred only4 paths4 endpoints
- GMPR2ProteinUNIPROT:Q9P2T1substrate ofInferred only4 paths4 endpoints
What the reference databases state
Chemical structure
- 6-thio-IMP has the functional parent IMPCompoundChEBI CHEBI:145875Inferred only
Statements
26 statements
26 statements · 1 reference database · Subject: IMP · Sources: Rhea
- 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide is converted to IMPCompoundRhea RHEA:18445Inferred only
- IDP is converted to IMPCompoundRhea RHEA:35207Inferred only
- IMP is converted to inosineCompoundRhea RHEA:27718Inferred only
- inosine is converted to IMPCompoundRhea RHEA:21140Inferred only
- IMP is converted to inosineCompoundRhea RHEA:21140Inferred only
- ITP is converted to IMPCompoundRhea RHEA:29399Inferred only
- ITP is converted to IMPCompoundRhea RHEA:77735Inferred only
- XMP is converted to IMPCompoundRhea RHEA:11708Inferred only
- IMP is converted to XMPCompoundRhea RHEA:11708Inferred only
- IMP is a substrate of ADSS1ProteinRhea RHEA:15753Inferred only
- IMP is a substrate of ADSS2ProteinRhea RHEA:15753Inferred only
- IMP is a substrate of GMPRProteinRhea RHEA:17185Inferred only
Show the remaining 14
- IMP is a substrate of GMPR2ProteinRhea RHEA:17185Inferred only
- IMP is a substrate of IMPDH1ProteinRhea RHEA:11708Inferred only
- IMP is a substrate of IMPDH2ProteinRhea RHEA:11708Inferred only
- IMP is a substrate of NT5CProteinRhea RHEA:27718Inferred only
- IMP is a substrate of NT5C1AProteinRhea RHEA:27718Inferred only
- IMP is a substrate of NT5C2ProteinRhea RHEA:69572Inferred only
- IMP is a substrate of NT5C2ProteinRhea RHEA:27718Inferred only
- IMP is a substrate of NT5C2ProteinRhea RHEA:69580Inferred only
- IMP is a substrate of NT5C2ProteinRhea RHEA:69584Inferred only
- IMP is a substrate of NT5C2ProteinRhea RHEA:69588Inferred only
- IMP is a substrate of NT5C2ProteinRhea RHEA:69592Inferred only
- IMP is a substrate of NT5C2ProteinRhea RHEA:69596Inferred only
- IMP is a substrate of NT5EProteinRhea RHEA:27718Inferred only
- IMP is transported by SLC25A36ProteinRhea RHEA:73647Inferred only
Reactions
22 reactions
IMP+NAD(1-)+waterXMP+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:11708CC BY 4.0Reference data
Catalysed by AMPD1 or AMPD3 or AMPD2
Reaction pageLeft to rightBalanced
Rhea RHEA:14777CC BY 4.0Reference data
IMP+L-aspartate+GTPN(6)-(1,2-dicarboxyethyl)-AMP+GDP+hydrogenphosphate+2hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:15753CC BY 4.0Reference data
N(6)-methyl-AMP+water+hydronIMP+methylamine
Catalysed by MAPDA
Reaction pageLeft to rightBalanced
Rhea RHEA:16001CC BY 4.0Reference data
IMP+ammonium+NADP(3-)GMP+NADPH(4-)+2hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:17185CC BY 4.0Reference data
IMP+diphosphate(3-)hypoxanthine+5-phospho-alpha-D-ribose 1-diphosphate
Catalysed by HPRT1
Reaction pageRight to leftBalanced
Rhea RHEA:17973CC BY 4.0Reference data
IMP+water5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
Catalysed by ATIC
Reaction pageRight to leftBalanced
Rhea RHEA:18445CC BY 4.0Reference data
IMP+waterhypoxanthine+D-ribose 5-phosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:20469CC BY 4.0Reference data
inosine+ATP(4-)IMP+ADP(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:21140CC BY 4.0Reference data
IMP+waterinosine+hydrogenphosphate
Catalysed by NT5E or NT5C2 or NT5C or NT5C1A
Reaction pageLeft to rightBalanced
Rhea RHEA:27718CC BY 4.0Reference data
ITP+waterIMP+diphosphate(3-)+hydron
Catalysed by ITPA
Reaction pageLeft to rightBalanced
Rhea RHEA:29399CC BY 4.0Reference data
IDP+waterIMP+hydrogenphosphate+hydron
Catalysed by ENTPD6 or ENTPD3 or ENTPD5 or ENTPD1 or NUDT16 or ENTPD2
Reaction pageLeft to rightBalanced
Rhea RHEA:35207CC BY 4.0Reference data
Where it reaches
7 systems, 13 regions, 39 tissues, 39 transporter routes — routes, not measurements: transporters known to carry IMP are expressed there, and no source reports it arriving.
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Other names
6 names
Resolves to: IMP
- Also called
- IMP dianioninosine 5'-phosphateinosine 5'-phosphate dianioninosine 5'-phosphate(2-)inosine 5'-phosphate(2−)
- Systematic name
- 5'-O-phosphonatoinosine