IMP

1. IMP + H2O = inosine + phosphate

Catalysed by NT5E, NT5C2, NT5C, NT5C1AOne of 7 routes

1. IMP + NAD(+) + H2O = XMP + NADH + H(+)

Catalysed by IMPDH2, IMPDH1

1. IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)

Catalysed by ADSS2, ADSS1

1. dGMP + inosine = 2'-deoxyguanosine + IMP

Catalysed by NT5C2

1. dIMP + inosine = 2'-deoxyinosine + IMP

Catalysed by NT5C2

1. dGMP + inosine = 2'-deoxyguanosine + IMP
2. dADP to dATP conversion

Catalysed by NT5C2mitochondrial matrix

1. IMP + H2O = inosine + phosphate
2. transport of adenosine and inosine (cytosol to extracellular)

Catalysed by NT5E, NT5C2, NT5C, NT5C1Aextracellular space, cytosolOne of 3 routes

1. IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)
2. IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)
3. acetyl-CoA:L-aspartate N-acetyltransferase

Catalysed by ADSS2, ADSS1, NAT8Lmitochondrial matrix

1. IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)
2. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)
3. a quinone + succinate = fumarate + a quinol

Catalysed by ADSS2 and 1 more