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Proteins/UNIPROT:Q9Y305
Mitochondrial acyl-CoA thioesterase. Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoA), regulating their respective intracellular levels. Regulates both mitochondrial lipid and amino acid metabolism..
Function from UniProtKB (Q9Y305), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
334 statements
334 statements · 7 reference databases · Subject: ACOT9 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways · Rows fetched: 300
11 reactions
water+propionyl-CoACHEBI:1146900+proton+propionic acid
Catalysed by ACOT7 or ACOT2 or BAAT or ACOT4 or ACOT1 or ACOT6 or ACOT9
Reaction pageLeft to rightBalancedEC 3.1.2.2mitochondrial matrix
Human-GEM MAR03799CC BY 4.0Reference data
2 names
Resolves to: ACOT9
Catalysed by ACOT9
Reaction pageLeft to rightBalancedEC 3.1.2.2mitochondrial matrix
Human-GEM MAR10374CC BY 4.0Reference data
hexadecanoyl-CoA+waterhexadecanoate+coenzyme A(4-)+hydron
Catalysed by ACOT7 or ACOT8 or PLA2G6 or ACAA2 or ACOT2 or PPT1 or BAAT or THEM4 or MBLAC2 or ACOT1 or THEM5 or ACOT4 and 5 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:16645CC BY 4.0Reference data
octanoyl-CoA+wateroctanoate+coenzyme A(4-)+hydron
Catalysed by ACOT7 or ACOT8 or ACAA2 or THEM4 or ACOT13 or ACOT9
Reaction pageLeft to rightBalanced
Rhea RHEA:30143CC BY 4.0Reference data
decanoyl-CoA+waterdecanoate+coenzyme A(4-)+hydron
Catalysed by ACOT7 or ACOT8 or ACAA2 or ACOT2 or THEM4 or ACOT1 or ACOT4 or ACOT13 or OLAH or ACOT9
Reaction pageLeft to rightBalanced
Rhea RHEA:40059CC BY 4.0Reference data
propanoyl-CoA+waterpropanoate+coenzyme A(4-)+hydron
Catalysed by ACOT8 or ACAA2 or ACOT9
Reaction pageLeft to rightBalanced
Rhea RHEA:40103CC BY 4.0Reference data
butanoyl-CoA+waterbutanoate+coenzyme A(4-)+hydron
Catalysed by ACOT8 or ACAA2 or ACOT11 or ACOT12 or ACOT13 or ACOT9
Reaction pageLeft to rightBalanced
Rhea RHEA:40111CC BY 4.0Reference data
tetradecanoyl-CoA+watertetradecanoate+coenzyme A(4-)+hydron
Catalysed by ACOT7 or ACOT8 or ACAA2 or ACOT2 or BAAT or THEM4 or MBLAC2 or ACOT1 or THEM5 or ACOT4 or ACOT11 or ACOT13 and 2 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:40119CC BY 4.0Reference data
4,8-dimethylnonanoyl-CoA+waterCHEBI:77063+coenzyme A(4-)+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:40223CC BY 4.0Reference data
2-methylpropanoyl-CoA+water2-methylpropanoate+coenzyme A(4-)+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:40799CC BY 4.0Reference data
isovaleryl-CoA+waterCHEBI:48942+coenzyme A(4-)+hydron
Catalysed by ACOT9
Reaction pageLeft to rightBalanced
Rhea RHEA:66984CC BY 4.0Reference data