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Proteins/UNIPROT:Q52LW3
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis..
Function from UniProtKB (Q52LW3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
55 statements
55 statements · 4 reference databases · Subject: ARHGAP29 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
3 names
Resolves to: ARHGAP29