Compound
hexadecanoate
A long-chain fatty acid anion that is the conjugate base of hexadecanoic acid (palmitic acid); major species at pH 7.3.
Definition from ChEBI (CHEBI:7896), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C16H31O2
- Mass
- 255.422 g/mol
- Charge
- -1
- InChIKey
- IPCSVZSSVZVIGE-UHFFFAOYSA-M
- SMILES
- CCCCCCCCCCCCCCCC(=O)[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
28 entities
28 entities reached.
0 reported hops28 assembled from the scaffold
- FABP5ProteinUNIPROT:Q01469transported byInferred only101 paths93 endpoints
- CD36ProteinUNIPROT:P16671transported byInferred only82 paths77 endpoints
- ACSL1ProteinUNIPROT:P33121substrate ofInferred only33 paths33 endpoints
- ACSL3ProteinUNIPROT:O95573substrate ofInferred only29 paths29 endpoints
- CYP4A11ProteinUNIPROT:Q02928metabolized byInferred only28 paths28 endpoints
- ASAH1ProteinUNIPROT:Q13510substrate ofInferred only26 paths26 endpoints
- ACSL4ProteinUNIPROT:O60488substrate ofInferred only23 paths23 endpoints
- SLC27A2ProteinUNIPROT:O14975substrate ofInferred only22 paths22 endpoints
- SLC27A4ProteinUNIPROT:Q6P1M0substrate of, transported byInferred only15 paths15 endpoints
- ALDH3A2ProteinUNIPROT:P51648metabolized byInferred only14 paths14 endpoints
- CYP4F11ProteinUNIPROT:Q9HBI6metabolized byInferred only13 paths13 endpoints
- PPT1ProteinUNIPROT:P50897substrate ofInferred only12 paths6 endpoints
Show the remaining 16
- ACSL6ProteinUNIPROT:Q9UKU0substrate ofInferred only11 paths11 endpoints
- ACSL5ProteinUNIPROT:Q9ULC5substrate ofInferred only11 paths11 endpoints
- CYP4V2ProteinUNIPROT:Q6ZWL3metabolized byInferred only10 paths10 endpoints
- ALDH3B1ProteinUNIPROT:P43353metabolized byInferred only9 paths9 endpoints
- ACSM1ProteinUNIPROT:Q08AH1substrate ofInferred only8 paths8 endpoints
- RPE65ProteinUNIPROT:Q16518substrate ofInferred only7 paths7 endpoints
- ACSBG1ProteinUNIPROT:Q96GR2substrate ofInferred only7 paths7 endpoints
- ASAH2ProteinUNIPROT:Q9NR71substrate ofInferred only7 paths7 endpoints
- ACSBG2ProteinUNIPROT:Q5FVE4substrate ofInferred only6 paths6 endpoints
- SLC27A3ProteinUNIPROT:Q5K4L6substrate ofInferred only6 paths6 endpoints
- FA2HProteinUNIPROT:Q7L5A8substrate ofInferred only5 paths5 endpoints
- ALDH3B2ProteinUNIPROT:P48448metabolized byInferred only5 paths5 endpoints
- ACER2ProteinUNIPROT:Q5QJU3substrate ofInferred only4 paths4 endpoints
- PPT2ProteinUNIPROT:Q9UMR5substrate ofInferred only4 paths4 endpoints
- SLC27A6ProteinUNIPROT:Q9Y2P4transported byInferred only4 paths4 endpoints
- NAAAProteinUNIPROT:Q02083substrate ofInferred only3 paths3 endpoints
What the reference databases state
Chemical structure
- 1-hexadecanoyl-sn-glycero-3-phospho-(3'-hexadecanoyl-1'-sn-glycerol) has the functional parent hexadecanoateCompoundChEBI CHEBI:232639Inferred only
- 1,2-diheptadecanoyl-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine has the functional parent hexadecanoateCompoundChEBI CHEBI:138220Inferred only
- 16-hydroxyhexadecanoate has the functional parent hexadecanoateCompoundChEBI CHEBI:55329Inferred only
- 3,7,11,15-tetramethylhexadecanoate has the functional parent hexadecanoateCompoundChEBI CHEBI:37257Inferred only
- a 1-hexadecanoyl-2-acylglycerol has the functional parent hexadecanoateCompoundChEBI CHEBI:156324Inferred only
- N-hexadecanoyl-L-phenylalanine has the functional parent hexadecanoateCompoundChEBI CHEBI:149699Inferred only
- N-hexadecanoyl-sphinga-4E,14Z-dienine has the functional parent hexadecanoateCompoundChEBI CHEBI:149633Inferred only
Statements
38 statements
38 statements · 1 reference database · Subject: hexadecanoate · Sources: Rhea
- hexadecanal is converted to hexadecanoateCompoundRhea RHEA:33739Inferred only
- hexadecanoate is converted to hexadecanalCompoundRhea RHEA:33739Inferred only
- hexadecanamide is converted to hexadecanoateCompoundRhea RHEA:62984Inferred only
- hexadecanoyl-CoA is converted to hexadecanoateCompoundRhea RHEA:16645Inferred only
- hexadecanoate is converted to hexadecanoyl-CoACompoundRhea RHEA:30751Inferred only
- hexadecanoyl-CoA is converted to hexadecanoateCompoundRhea RHEA:51716Inferred only
- hexadecanoate is converted to hexadecanoyl-CoACompoundRhea RHEA:51716Inferred only
- hexadecanoate is metabolised by ALDH3A2ProteinRhea RHEA:33739Inferred only
- hexadecanoate is metabolised by ALDH3B1ProteinRhea RHEA:33739Inferred only
- hexadecanoate is metabolised by ALDH3B2ProteinRhea RHEA:33739Inferred only
- hexadecanoate is metabolised by CYP4A11ProteinRhea RHEA:40199Inferred only
- hexadecanoate is metabolised by CYP4F11ProteinRhea RHEA:40199Inferred only
Show the remaining 26
- hexadecanoate is metabolised by CYP4V2ProteinRhea RHEA:40199Inferred only
- hexadecanoate is a substrate of ACER2ProteinRhea RHEA:38891Inferred only
- hexadecanoate is a substrate of ACSBG1ProteinRhea RHEA:30751Inferred only
- hexadecanoate is a substrate of ACSBG2ProteinRhea RHEA:30751Inferred only
- hexadecanoate is a substrate of ACSL1ProteinRhea RHEA:30751Inferred only
- hexadecanoate is a substrate of ACSL3ProteinRhea RHEA:30751Inferred only
- hexadecanoate is a substrate of ACSL4ProteinRhea RHEA:30751Inferred only
- hexadecanoate is a substrate of ACSL5ProteinRhea RHEA:30751Inferred only
- hexadecanoate is a substrate of ACSL6ProteinRhea RHEA:30751Inferred only
- hexadecanoate is a substrate of ACSM1ProteinRhea RHEA:30751Inferred only
- hexadecanoate is a substrate of ASAH1ProteinRhea RHEA:38891Inferred only
- hexadecanoate is a substrate of ASAH2ProteinRhea RHEA:38891Inferred only
- hexadecanoate is a substrate of FA2HProteinRhea RHEA:38551Inferred only
- hexadecanoate is a substrate of NAAAProteinRhea RHEA:38891Inferred only
- hexadecanoate is a substrate of PPT1ProteinRhea RHEA:84103Inferred only
- hexadecanoate is a substrate of PPT1ProteinRhea RHEA:84099Inferred only
- hexadecanoate is a substrate of PPT2ProteinRhea RHEA:84099Inferred only
- hexadecanoate is a substrate of RPE65ProteinRhea RHEA:31775Inferred only
- hexadecanoate is a substrate of SLC27A2ProteinRhea RHEA:30751Inferred only
- hexadecanoate is a substrate of SLC27A3ProteinRhea RHEA:30751Inferred only
- hexadecanoate is a substrate of SLC27A4ProteinRhea RHEA:30751Inferred only
- hexadecanoate is transported by CD36ProteinRhea RHEA:45256Inferred only
- hexadecanoate is transported by FABP5ProteinRhea RHEA:45256Inferred only
- hexadecanoate is transported by SLC27A1ProteinRhea RHEA:45256Inferred only
- hexadecanoate is transported by SLC27A4ProteinRhea RHEA:45256Inferred only
- hexadecanoate is transported by SLC27A6ProteinRhea RHEA:45256Inferred only
Reactions
94 reactions
all-trans-retinyl hexadecanoate+waterall-trans-retinol+hexadecanoate+hydron
Catalysed by PNLIP or PNPLA4 or LIPE
Reaction pageLeft to rightBalanced
Rhea RHEA:13933CC BY 4.0Reference data
hexadecanoyl-CoA+waterhexadecanoate+coenzyme A(4-)+hydron
Catalysed by ACOT7 or ACOT8 or PLA2G6 or ACAA2 or ACOT2 or PPT1 or BAAT or THEM4 or MBLAC2 or ACOT1 or THEM5 or ACOT4 and 5 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:16645CC BY 4.0Reference data
S-hexadecanoyl-L-cysteinyl-[protein]+waterL-cysteinyl-[protein]+hexadecanoate+hydron
Catalysed by CLN5 or LYPLA1 or LYPLA2 or PPT1 or ABHD17B or LYPLAL1 or DESI1 or ABHD17C or CPT1C or ABHD17A or DESI2 or ABHD10
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:19233CC BY 4.0Reference data
11-cis-retinyl hexadecanoate+water11-cis-retinol+hexadecanoate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:19697CC BY 4.0Reference data
all-trans-retinyl hexadecanoate+waterCHEBI:50211+hexadecanoate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:21508CC BY 4.0Reference data
hexadecanoate+2hydrogen peroxide+hydronCHEBI:17302+carbon dioxide+3water
Reaction pageDirection not assertedBalanced
Rhea RHEA:23960CC BY 4.0Reference data
hexadecanoate+ATP(4-)+coenzyme A(4-)hexadecanoyl-CoA+AMP+diphosphate(3-)
Catalysed by SLC27A2 or ACSL4 or ACSL3 or ACSL1 or ACSM1 or ACSBG2 or SLC27A3 or SLC27A4 or ACSBG1 or ACSL6 or ACSL5
Reaction pageLeft to rightBalanced
Rhea RHEA:30751CC BY 4.0Reference data
all-trans-retinyl hexadecanoate+water11-cis-retinol+hexadecanoate+hydron
Catalysed by RPE65
Reaction pageDirection not assertedBalanced
Rhea RHEA:31775CC BY 4.0Reference data
CHEBI:64976+waterCHEBI:16933+hexadecanoate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:33543CC BY 4.0Reference data
CHEBI:64975+waterlanosterol+hexadecanoate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:33547CC BY 4.0Reference data
hexadecanoate+NADH(2-)+2hydronhexadecanal+NAD(1-)+water
Catalysed by ALDH3B1 or ALDH3B2 or ALDH3A2
Reaction pageReversibleBalanced
Rhea RHEA:33739CC BY 4.0Reference data
N-hexadecanoyl-(4R)-hydroxysphinganine+water(4R)-hydroxysphinganine+hexadecanoate
Reaction pageDirection not assertedBalanced
Rhea RHEA:33755CC BY 4.0Reference data
Where it reaches
10 systems, 24 regions, 121 tissues, 147 transporter routes — routes, not measurements: transporters known to carry hexadecanoate are expressed there, and no source reports it arriving.
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Other names
11 names
Resolves to: hexadecanoate
- Also called
- (16:0)1-hexyldecanoate1-pentadecanecarboxylateCH3-[CH2]14-COO(-)CH3‒[CH2]14‒COO−FA(16:0)Hexadecanoic acid, ion(1-)n-hexadecanoaten-hexadecoatepalmitatepentadecanecarboxylate