Loading the page.
Proteins/UNIPROT:P78560
Adapter protein that associates with PIDD1 and the caspase CASP2 to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis. Also recruits CASP2 to the TNFR-1 signaling complex through its interaction with RIPK1 and TRADD and may play a role in the tumor necrosis factor-mediated signaling pathway..
Function from UniProtKB (P78560), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
230 statements
230 statements · 4 reference databases · Subject: CRADD · Sources: gene ontology, Hetionet, Reactome, WikiPathways
3 names
Resolves to: CRADD