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Proteins/UNIPROT:Q8WXI4
Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway..
Function from UniProtKB (Q8WXI4), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
16 statements
16 statements · 6 reference databases · Subject: ACOT11 · Sources: gene ontology, Hetionet, Human Protein Atlas, Reactome, Rhea, WikiPathways
6 reactions
water+MAM03007cCHEBI:1146900+proton+MAM03568c
Catalysed by ACOT7 or ACOT13 or ACOT11 or ACOT1
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR11749CC BY 4.0Reference data
water+MAM03689cCHEBI:1146900+proton+MAM03687c
Catalysed by
8 names
Resolves to: ACOT11
Reaction pageLeft to rightBalancedEC 3.1.2.2, 3.1.2.27, 3.1.2.-cytosol
Human-GEM MAR12744CC BY 4.0Reference data
hexadecanoyl-CoA+waterhexadecanoate+coenzyme A(4-)+hydron
Catalysed by ACOT7 or ACOT8 or PLA2G6 or ACAA2 or ACOT2 or PPT1 or BAAT or THEM4 or MBLAC2 or ACOT1 or THEM5 or ACOT4 and 5 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:16645CC BY 4.0Reference data
dodecanoyl-CoA+waterdodecanoate+coenzyme A(4-)+hydron
Catalysed by ACOT7 or ACOT8 or ACAA2 or ACOT2 or BAAT or THEM4 or MBLAC2 or ACOT1 or ACOT4 or ACOT11 or ACOT13 or OLAH
Reaction pageLeft to rightBalanced
Rhea RHEA:30135CC BY 4.0Reference data
butanoyl-CoA+waterbutanoate+coenzyme A(4-)+hydron
Catalysed by ACOT8 or ACAA2 or ACOT11 or ACOT12 or ACOT13 or ACOT9
Reaction pageLeft to rightBalanced
Rhea RHEA:40111CC BY 4.0Reference data
tetradecanoyl-CoA+watertetradecanoate+coenzyme A(4-)+hydron
Catalysed by ACOT7 or ACOT8 or ACAA2 or ACOT2 or BAAT or THEM4 or MBLAC2 or ACOT1 or THEM5 or ACOT4 or ACOT11 or ACOT13 and 2 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:40119CC BY 4.0Reference data