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Proteins/UNIPROT:Q6Q788
Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin..
Function from UniProtKB (Q6Q788), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
72 statements
72 statements · 4 reference databases · Subject: APOA5 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
5 names
Resolves to: APOA5