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Proteins/UNIPROT:Q8WYK0
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Preferentially hydrolyzes acetyl-CoA..
Function from UniProtKB (Q8WYK0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
11 statements
11 statements · 5 reference databases · Subject: ACOT12 · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
7 reactions
CHEBI:15351+wateracetate+CHEBI:1146900+proton
Catalysed by ACOT12
Reaction pageLeft to rightBalancedEC 3.1.2.1cytosol
Human-GEM MAR04093CC BY 4.0Reference data
CHEBI:15351+wateracetate+CHEBI:1146900+proton
Catalysed by ACOT12
10 names
Resolves to: ACOT12
Human-GEM MAR04095CC BY 4.0Reference data
water+CHEBI:27540CHEBI:1146900+proton+MAM02120c
Catalysed by ACOT12
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR11544CC BY 4.0Reference data
butanoyl-CoA+waterbutyric acid+CHEBI:1146900+proton
Catalysed by ACOT12
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR20169CC BY 4.0Reference data
acetyl-CoA+wateracetate+coenzyme A(4-)+hydron
Catalysed by ACOT8 or ACAA2 or ACOT12
Reaction pageLeft to rightBalanced
Rhea RHEA:20289CC BY 4.0Reference data
butanoyl-CoA+waterbutanoate+coenzyme A(4-)+hydron
Catalysed by ACOT8 or ACAA2 or ACOT11 or ACOT12 or ACOT13 or ACOT9
Reaction pageLeft to rightBalanced
Rhea RHEA:40111CC BY 4.0Reference data
hexanoyl-CoA+waterhexanoate+coenzyme A(4-)+hydron
Catalysed by ACOT8 or ACAA2 or ACOT12 or ACOT13
Reaction pageLeft to rightBalanced
Rhea RHEA:40115CC BY 4.0Reference data